Main Article Content
Anti-neoplastic drugs, waste management, tertiary hospitals
Background: In order to attain persistent environmental sustainability and safeguard public health, it is imperative to implement suitable management practices for healthcare waste. Consequently, healthcare personnel must be adequately trained in the proper handling of chemical waste arising from anti-neoplastic chemotherapy, as it presents potential risks to the well-being of both staff members, patients, and the surrounding environment.
Aims: The aim of this study is to assess the level of knowledge and attitudes regarding waste management practices for anti-neoplastic drugs in tertiary hospitals located in Karachi.
Methods: A questionnaire was developed with the purpose of assessing individuals' knowledge and awareness regarding the management of anti-neoplastic waste. Data was obtained from the oncology departments of all the hospitals involved in the study. A comprehensive analysis was undertaken to summarize the findings of the survey.
Results: The findings indicate a notable deficiency in the participants' understanding of appropriate management of waste contaminated with anti-neoplastic drugs, as well as their attitudes towards the utilization of Personal Protective Equipment (PPE). When queried about the proper disposal of waste products contaminated with anti-neoplastic drugs, only 22% of the respondents expressed agreement with the necessity of segregating and individually packaging all the contaminated materials.
Conclusion: The findings of this survey provide evidence in favor of implementing a more extensive waste management programme that would be sustained through regular training and supervision.
2. Sial, N., Ahmad, M., Hussain, M. S., Iqbal, M. J., Hameed, Y., Khan, M., ... & Asif, H. M. (2021). CTHRC1 expression is a novel shared diagnostic and prognostic biomarker of survival in six different human cancer subtypes. Scientific reports, 11(1), 19873.
3. Farooqi, U. G., Shahbaz, N., Khan, F. A., Aleem, S. A., Ali, M., & Kaleem, U. (2022). Investigating Healthcare Waste Regulation: Employees’ Knowledge, Perceptions and Practices with Regard to Recycling. Annals of the Romanian Society for Cell Biology, 26(01), 1189-1195.
4. Sial, N., Saeed, S., Ahmad, M., Hameed, Y., Rehman, A., Abbas, M., ... & Khan, M. R. (2021). Multi-omics analysis identified TMED2 as a shared potential biomarker in six subtypes of human cancer. International Journal of General Medicine, 7025-7042.
5. Krstev, S., Perunicić, B., & Vidaković, A. (2003). Work practice and some adverse health effects in nurses handling antineoplastic drugs. La Medicina del lavoro, 94(5), 432-439.
6. Kyprianou, M., Kapsou, M., Raftopoulos, V., & Soteriades, E. S. (2010). Knowledge, attitudes and beliefs of Cypriot nurses on the handling of antineoplastic agents. European Journal of Oncology Nursing, 14(4), 278-282.
7. NIOSH, B. G., Connor, T., & McDiarmid, M. (2004). NIOSH alert: preventing occupational exposures to antineoplastic and other hazardous drugs in health care settings. Inst Occup, 58(6).
8. Usman, M., Okla, M. K., Asif, H. M., AbdElgayed, G., Muccee, F., Ghazanfar, S., ... & Hameed, Y. (2022). A pan-cancer analysis of GINS complex subunit 4 to identify its potential role as a biomarker in multiple human cancers. American Journal of Cancer Research, 12(3), 986.
9. Polovich, M. (2010). Nurses' use of hazardous drug safe handling precautions.
10. Hameed, Y., Usman, M., Liang, S., & Ejaz, S. (2021). Novel diagnostic and prognostic biomarkers of colorectal cancer: capable to overcome the heterogeneity-specific barrier and valid for global applications. Plos one, 16(9), e0256020.
11. Sial, N., Rehman, J. U., Saeed, S., Ahmad, M., Hameed, Y., Atif, M., ... & Ambreen, A. (2022). Integrative analysis reveals methylenetetrahydrofolate dehydrogenase 1-like as an independent shared diagnostic and prognostic biomarker in five different human cancers. Bioscience Reports, 42(1), BSR20211783.
12. Turk, M., Davas, A., Çiçeklioglu, M., Saçaklioglu, F., & Mercan, T. (2004). Knowledge, attitude and safe behaviour of nurses handling cytotoxic anticancer drugs in Ege University Hospital. Asian Pac J Cancer Prev, 5(2), 164-8.
13. Yanqin, Y., Dezhong, X., Bo, W., Xianni, W., Xiaoli, Q., & Xianghai, M. (2012). An investigation into the occupational protection status of clinical nursing staff exposed to anti-tumor drugs. Journal of Medical Colleges of PLA, 27(2), 113-119.
14. Ziegler, E., Mason, H. J., & Baxter, P. J. (2002). Occupational exposure to cytotoxic drugs in two UK oncology wards. Occupational and environmental medicine, 59(9), 608-612.