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Nephrotic syndrome, nephropathy, IgA, case report
Immunoglobulin A (IgA) kidney disease is considered a primary glomerular pathology that occurs most globally. Within its clinical characteristics, micro and macroscopic, recurrent and transient hematuria may occur, in addition, in some asymptomatic cases. The main objective of the article focuses on describing the atypical clinical presentation of IgA nephropathy. The methodology was carried out from a descriptive study, by collecting data provided by the clinical history. Likewise, a data collection was carried out in digital databases such as: PubMed, Science Direct, Elseiver and Scopus, which serve to compare the therapeutic scheme used and the clinical manifestations associated with the pathology. The results obtained showed that an initial search showed a total of 139 articles, of which, after their respective analysis, a total of 15 articles were included. The development of a study or clinical case report is of great relevance to establish diagnostic processes and treatment schemes according to the clinical characteristics of patients with IgA nephropathy and nephrotic syndrome. The clinical picture presented by the patient corresponded to hemoptysis 24 hours ago, accompanied by a sensation of elevated temperature and dyspnea, in addition, proteinuria was observed. Treatment at discharge corresponded to a general diet, hygienic-dietary measures and control of warning signs, losartan, prednisone, simvastatin, furosemide and rivaroxaban.
2. Aroca G, Arroyo A, Martínez E, Espítatela Z, Ramos E, García R. Clinical-pathological characterization in patients with histological diagnosis of IgA nephropathy in the Colombian Caribbean Region. Gac Méd Caracas. 2021; 129(1): p. 1-7.
3. Schossler L, Brandenburg T, Litcheteneker K, Roberto R, Kazuyuki S. IgA nephropathy: Analysis of its Clinical Course in a Nephrology Center. Revista Nefrologia Argentina. 2019; 17(2).
4. American Kidney Fund. IgA nephropathy. [Online]; 2020. Available in: https://www.kidneyfund.org/es/todo-sobre-los-rinones/los-tipos-de-enfermedad-renal/la-nefropatia-por-iga.
5. Stanford Medicine. Immunoglobulin A (IgA) nephropathy. [Online]; 2019. Available from: https://www.stanfordchildrens.org/es/topic/default?id=immunoglobulin-a-iga-nephropathy-85-P04580.
6. Brien F. Immunoglobulin A nephropathy [Online]; 2021. Available in: https://www.msdmanuals.com/es-ec/professional/trastornos-urogenitales/glomerulopat%C3%ADas/nefropat%C3%ADa-por-inmunoglobulina-a#:~:text=La%20nefropat%C3%ADa%20por%20immunoglobulinas%20A,pron%C3%B3stico%20en%20general%20es%20bueno.
7. Orozco R, Fierro A, Contreras L, Wash A. Clinical-anatomopathological case: The various presentations of IgA nephropathy. Revista Médica Clínica Las Condes. 2010; 21(4): p. 655-661.
8. Coronel V, Mora S, Domínguez L, Corado J, Zibaoui P. Clinical pathological characteristics and evolution of IgA nephropathy in a hospital series of Venezuelan children. Clinical Research. 2007.
9. Duran S, field L. IgA nephropathy, the most common glomerulopathy. Cuban Journal of Pediatrics. 2015; 87(3): p. 350-361.
10. Lococo B, Alberton V, Fazzini B, Smuclir A, Morales D, Malvar A. IgA nephropathy. Review and therapeutic conduct regarding a clinical case. Rev Nefrol Dial Traspl. 2016; 36(2).
11. Gadola L, Cabrera J, Acosta N, Panuncio A, Haydé M, Coria V, et al. IgA nephropathy in Uruguay: clinical presentation and evolution. Revista Médica del Uruguay. 2015; 31(1).
12. Cheung C, Barratt J. Clinical presentation and diagnosis of IgA nephropathy. UpToDate. [Online]; 2020. Available in: https://revistasanitariadeinvestigacion.com/nefropatia-por-lga/.
13. Natale P, Palmer S, Ruospo M, Saglimbene V. Immunosuppressive agents for the treatment of IgA nephropathy. Cochrane Database Syst Rev. 2020; 3.
14. Forero J, Torres L, Duque N. Immunoglobulin A nephropathy in pediatrics, clinical outcomes with different management schemes. Colombian Journal of Nephrology. 2021; 8(1).
15. Merino E, Borrega FJ, Garcia MJ. IgA nephropathy: short-term effects of prednisone treatment on proteinuria, renal function, and relationship to the Oxford classification. Journal of nephrology. 2021; 41(1): p. 1-90.