LIPIDOMIC ANALYSIS OF OMEGA-3 FATTY ACIDS IMPLICATIONS FOR CARDIOVASCULAR HEALTH- A DETAILED STUDY ON THE BENEFICIAL EFFECTS OF OMEGA-3 FATTY ACIDS

Main Article Content

Dr Muhammad Shahbaz
Dr Muhammad Amir
Dr Sabeen Islam
Dr Asnad

Keywords

BMI, HDL, RCT, Omega-3, Fatty Acids, CVD, Patients

Abstract

Introduction: Cardiovascular health stands as a paramount concern in contemporary medicine and public health. The prevalence of cardiovascular diseases (CVDs) and their associated risk factors continue to pose a substantial burden on global healthcare systems and overall well-being.


Objectives: The basic aim of the study is to find the lipidomic analysis of omega-3 fatty acids and its implications for cardiovascular health as a detailed study on the beneficial effects of omega-3 fatty acids.


 Material and methods: This Randomized Controlled Trial (RCT) was conducted in Mohtarma Benazir Bhutoo Shaheed Medical College Mirpur AJK from January 2023 to June 2023. A total of 220 adult participants was added in the study. Data collection in this randomized controlled trial (RCT) involves a comprehensive and systematic approach to gather a wide range of information essential for assessing the impact of omega-3 fatty acid supplementation on cardiovascular health.


Results: The study included 220 adult participants, evenly distributed between the treatment (omega-3 supplementation) and control (placebo) groups, with an average age of 50 years and a balanced gender distribution. Approximately 60% of participants in both groups had a history of hypertension at baseline. Elevated cholesterol levels (LDL cholesterol ≥ 130 mg/dL) were observed in 45% of participants in both groups. About 30% of participants had a family history of cardiovascular diseases. 20% of participants in both groups reported a history of smoking. The average BMI was 28 kg/m², indicating a generally overweight population.


Conclusion: It is concluded that this study provides valuable insights into the potential cardiovascular benefits of omega-3 fatty acid supplementation, including reductions in blood pressure, favorable lipidomic changes, and shifts towards an anti-inflammatory state.

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