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Sadaf Khalid
Komal Khalid
Afsar Ali Bhatti
Zahid Iqbal


inguinal hernia repair, prophylactic antibiotics, surgical site infection, systematic review, meta-analysis


Background: Inguinal hernia repair is a frequently performed surgical procedure, and the effectiveness of prophylactic antibiotics in preventing postoperative surgical site infections (SSIs) is a topic of ongoing investigation.

Objectives: This systematic review aims to assess the impact of prophylactic antibiotics on reducing SSIs after inguinal hernia repair through a comprehensive meta-analysis of available literature.

Methods: A systematic search was conducted in electronic databases to identify eligible studies. For this study, Preferred Reporting Items guideline for conducting this systematic review analysis (PRISMA) was followed. Electronic articles from January 2022 to April 2023 were searched on PUB Med, online Willey library, and Science Direct site. A systematic and exhaustive search of electronic databases such as PubMed, Embase, Scopus, and the Cochrane Library was conducted. The search strategy was constructed using a combination of relevant keywords and medical subject headings (MeSH) related to inguinal hernia repair, prophylactic antibiotics, surgical site infections, and associated concepts.

Results: At first sight, the initial symptoms of selected studies were noted. A systematic search of electronic databases from January 2022 to April 2023 identified a total of 25 potentially relevant articles. After title and abstract screening, 7 articles were selected for full-text review. Following the full-text assessment, 10 articles met the predefined inclusion criteria and were included in the systematic review.

Conclusion: It is concluded that our systematic review provides valuable insights into the role of prophylactic antibiotics in inguinal hernia repair. While the evidence suggests benefits in reducing SSIs, clinicians should consider patient risk profiles, antibiotic choice, and potential adverse events when making decisions.

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