Monotherapy Of Tamsulosin Vs Monotherapy of Solifenacin in The Treatment Of Ureter Stent Discomforts In Urology Patients: A Retrospective Study

Main Article Content

Dharani Prasad P
N.Anil kumar
Sai Gowtham K
Sai Chaitanya K
Chandra Priya P
Tejaswani K
Maneesha P
Vishnu Teja P
Mallikarjuna B P

Keywords

Ureteral Stent Symptom Questionnaire (USSQ), Double J stent (DJ-STENT), Lower Urinary Tract Symptoms (LUTS), Pre-Cutaneous Nephrolithotomy (PCNL), Ureteroscopy and Laser stone Fragmentation (URSL), Stent Related Symptoms (SRS), Muscarinic Receptor Antagonist (MRA).

Abstract

DJ stent placement is a common and necessary urological procedure that can be used in a variety of ways to treat a variety of urinary tract conditions. It can cause lower urinary tract symptoms (LTUS). Pharmacologic therapy is one of several experiments that have been conducted to alleviate these symptoms, specifically the use of alpha-1A blockers (tamsulosin) and antimuscarinics (solifenacin) in the treatment of LUTS associated with DJ stents. The aim of our study was evaluating the monotherapy of tamsulosin vs monotherapy of solifenacin in ureter stent discomfort patients in department of Urology Sri Venkateswara Institute of Medical Sciences south Indian tertiary care teaching hospital Tirupati, Andhra Pradesh. A retrospective study was conducted in 187 patients with ureter stent discomfort patients. The data collected from 187 patients was initially assessed for their USSQ quesionarries, QoL and efficacy of monotherapy of tamsulosin vs monotherapy of solifenacin was assessed.

Abstract 222 | PDF Downloads 170

References

1. Zimskind PD, Fetter TR, Willierson JL. ‘Clinical use of long-term indwelling silicone rubber ureteral splints inserted cystoscopically.’ Journal of Urology 1967; 97:840-844.
2. Chew BH, Knudsen BE, Nott L, et al (2007) Pilot study of ureteral movement in stented patients: the first step in understanding dynamic ureteral anatomy to improve stent comfort. J Endourol 21:1069–1075.
3. Joshi HB, et al. Ureteral stent symptom questionnaire: development and validation of the multidimensional quality of life measure. J Urol. 2003;169(3):10604. The ureteral stent symptoms questionnaire (USSQ) described and validated in this paper is the only validated measure to study specifically stent-related symptoms.
4. Joshi HB, Okeke A, News N, Keeley FX Jr, Timoney AG.Characterization of urinary symptoms in patients with ureteral stents. Urology. 2002;59(4):511–6.
5. Joshi HB, Stainthorpe A, Keeley FX Jr, MacDonagh R, Timoney AG. Indwelling ureteral stents: evaluation of the quality of life to aid outcome analysis. J Endourol. 2001;15(2):151–4.
6. Beiko DT, Watterson JD, Knudsen BE, Nott L, Pautler SE, Brock GB, et al. Second Prize: Double-Blind Randomized Controlled Trial Assessing the Safety and Efficacy of Intravesical Agents for Ureteral Stent Symptoms after Extracorporeal Shockwave Lithotripsy. Journal of endourology. 2004;18(8):723-30.
7. Damiano R, Autorino R, De Sio M, Giacobbe A, Palumbo IM, D’Armiento M. Effect of tamsulosin in preventing ureteral stent-related morbidity: a prospective study. Journal of endourology. 2008;22(4):651-6.
8. Joshi HB, Newns N, Stainthorpe A, MacDonagh RP, Keeley FX Jr, Timoney AG (2003) Ureteral stent symptom questionnaire: development and validation of the multidimensional quality of life measure. J Endocrinol 169:1060–1064.
9. Deliveliotis C, Chrisofos M, Gougousis E, Papatsoris A, Dellis A, Varkarakis IM, et al. Is there a role for alpha1-blockers in treating double-J stent-related symptoms? Urology 2006; 67:35-9.
10. Shen, Howard (2008). Illustrated Pharmacology Memory Cards: PharMnemonics. Minireview. p. 13. ISBN 978-1-59541-101-3.
11. Lewis, Sharon Mantik (5 December 2013). Medical-surgical nursing: assessment and management of clinical problems. Dirksen, Shannon Ruff,Heitkemper, Margaret M. (Margaret McLean), Bucher, Linda, Harding, Mariann (Ninth ed.). St. Louis, Missouri. ISBN 978-0-323-10089-2. OCLC 228373703.
12. Jasek, W, ed. (2007). Austria-Codex (in German) (62nd ed.). Vienna: Österreichischer Apothekerverlag. pp. 8659–62. ISBN 978-3-85200-181-4.

Most read articles by the same author(s)