COMPARATIVE EVALUATION OF ENDOSCOPIC AND MICROSCOPIC TECHNIQUES FOR TRANSSPHENOIDAL SURGERY IN PITUITARY ADENOMAS
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Keywords
pituitary adenoma, transsphenoidal surgery, endoscopic surgery, microscopic surgery, residual tumour, extent of resection
Abstract
Background: Transsphenoidal surgery is a principal operative approach for many pituitary adenomas. Endoscopic and microscopic techniques differ in visualization and access to the sellar and parasellar regions.
Objective: To compare endoscopic and microscopic transsphenoidal surgery with respect to postoperative residual tumour, extent of resection, selected complications, and hospital stay.
Methods: The study describes 85 patients: 43 in an endoscopic group and 42 in a microscopic group.
Results:A total of 85 patients with pituitary adenomas were included in the comparative analysis, comprising 43 patients who underwent endoscopic transsphenoidal surgery and 42 patients who underwent microscopic transsphenoidal surgery. Residual tumour was reported in 8 patients (18.6%) in the endoscopic group compared with 14 patients (33.3%) in the microscopic group. Accordingly, the reported gross-total resection rates were 81.4% and 66.7%, respectively.
Conclusion: No clinical conclusion about superiority can be drawn from simulated figures. A valid comparison requires verified patient-level data, prespecified outcome definitions, and appropriate analysis of confounding factors.
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