POST-INFECTIOUS OPSOCLONUS-MYOCLONUS ATAXIA SYNDROME IN RICKETTSIAL DISEASE
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Keywords
opsoclonus-myoclonus-ataxia syndrome, ricketssial illness
Abstract
Background: Opsoclonus-Myoclonus Ataxia (OMA) syndrome is a rare neurological disorder that occurs in approximately 1 in 5,000,000 individuals per year in the general population. We report three cases of OMA syndrome presenting post-rickettsial infection.
Discussion: The prevalence of rickettsial infections in the South Indian population is estimated to be around 10% to 30% among acute undifferentiated febrile illnesses. While headache and encephalitis are well-known neurological manifestations of this infection, "dancing feet–dancing eyes" (OMA) is rarely seen.
Methods & Results: We present three such unique cases. Rickettsial disease was confirmed using the Weil-Felix test. All patients were thoroughly screened for underlying paraneoplastic conditions. Every patient responded exceptionally well to a combination of pulse intravenous methylprednisolone (IVMP) and doxycycline.
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