THREE-DIMENSIONAL PRINTING AND PATIENT-SPECIFIC SOLUTIONS IN ORTHOPEDIC SURGERY: A NARRATIVE REVIEW
Main Article Content
Keywords
Three-dimensional printing; additive manufacturing; orthopedics; patient-specific instrumentation; surgical planning; custom implants; tissue engineering
Abstract
Three-dimensional printing, also known as additive manufacturing, has emerged as an important technology in orthopedic surgery. Unlike conventional subtractive manufacturing, three-dimensional printing creates physical objects layer by layer from digital models. This approach enables the production of patient-specific anatomical models, surgical guides, instruments, implants, orthoses, and tissue-engineering scaffolds. Orthopedic surgery is particularly suited to this technology because bones can be accurately reconstructed from computed tomography images and converted into printable models. Evidence published between 2010 and 2019 suggests that three-dimensional printing may improve the understanding of complex anatomy, facilitate preoperative planning, reduce operative time and fluoroscopic exposure, and increase the accuracy of selected procedures. Applications have been described in orthopedic trauma, arthroplasty, spinal surgery, deformity correction, orthopedic oncology, and medical education. Nevertheless, widespread adoption is limited by production time, cost, image-segmentation errors, material restrictions, regulatory requirements, and a shortage of high-quality comparative clinical studies. This narrative review discusses the workflow, principal orthopedic applications, potential benefits, limitations, and future directions of three-dimensional printing based on literature published from 2010 to 2019.
References
2. Murr LE, Gaytan SM, Martinez E, Medina F, Wicker RB. Next-generation orthopaedic implants by additive manufacturing using electron beam melting. International Journal of Biomaterials. 2012;2012:245727.
3. Auricchio F, Marconi S. 3D printing: clinical applications in orthopaedics and traumatology. EFORT Open Reviews. 2016;1(5):121–127.
4. Murr LE, Gaytan SM, Medina F, et al. Next-generation biomedical implants using additive manufacturing of complex, cellular and functional mesh arrays. Philosophical Transactions of the Royal Society A. 2010;368(1917):1999–2032.
5. Eltorai AEM, Nguyen E, Daniels AH. Three-dimensional printing in orthopedic surgery. Orthopedics. 2015;38(11):684–687.
6. Tack P, Victor J, Gemmel P, Annemans L. 3D-printing techniques in a medical setting: a systematic literature review. Biomedical Engineering Online. 2016;15:115.
7. Wong TM, Jin J, Lau TW, et al. The use of three-dimensional printing technology in orthopaedic surgery: a review. Journal of Orthopaedic Surgery. 2017;25(1):1–7.
8. Wang X, Xu S, Zhou S, et al. Topological design and additive manufacturing of porous metals for bone scaffolds and orthopaedic implants: a review. Biomaterials. 2016;83:127–141.
9. Ahangar P, Cooke ME, Weber MH, Rosenzweig DH. Current biomedical applications of 3D printing and additive manufacturing. Applied Sciences. 2019;9(8):1713.
10. Javaid M, Haleem A. Additive manufacturing applications in orthopaedics: a review. Journal of Clinical Orthopaedics and Trauma. 2018;9(3):202–206.
11. Vaish A, Vaish R. 3D printing and its applications in orthopedics. Journal of Clinical Orthopaedics and Trauma. 2018;9(Suppl 1):S74–S75.
12. Wu AM, Shao ZX, Wang JS, et al. The accuracy of a method for printing three-dimensional spinal models. PLoS One. 2015;10(4):e0124291.
13. Lal H, Patralekh MK. 3D printing and its applications in orthopaedic trauma: a technological marvel. Journal of Clinical Orthopaedics and Trauma. 2018;9(3):260–268.
14. Wilcox B, Mobbs RJ, Wu AM, Phan K. Systematic review of 3D printing in spinal surgery: the current state of play. Journal of Spine Surgery. 2017;3(3):433–443.
15. Diment LE, Thompson MS, Bergmann JHM. Clinical efficacy and effectiveness of 3D printing: a systematic review. BMJ Open. 2017;7:e016891.
16. Hoang D, Perrault D, Stevanovic M, Ghiassi A. Surgical applications of three-dimensional printing: a review of the current literature and how to get started. Annals of Translational Medicine. 2016;4(23):456.
17. Tetsworth K, Block S, Glatt V. Putting 3D modelling and 3D printing into practice: virtual surgery and preoperative planning to reconstruct complex post-traumatic skeletal deformities and defects. SICOT-J. 2017;3:16.
18. Zeng C, Xiao J, Wu Z, Huang W. Evaluation of three-dimensional printing for internal fixation of unstable pelvic fracture from minimal invasive para-rectus abdominis approach: a preliminary report. International Journal of Clinical and Experimental Medicine. 2015;8(8):13039–13044.
19. Bizzotto N, Sandri A, Regis D, Romani D, Tami I, Magnan B. Three-dimensional printing of bone fractures: a new tangible realistic way for preoperative planning and education. Surgical Innovation. 2015;22(5):548–551.
20. Trauner KB. The emerging role of 3D printing in arthroplasty and orthopedics. Journal of Arthroplasty. 2018;33(8):2352–2354.

