COMPARING THE EFFECT OF INTRAVENOUS LIDOCAINE AND LIDOCAINE WITH DEXAMETHASONE ON INCIDENCE OF POSTOPERATIVE SORE THROAT AFTER ENDOTRACHEAL INTUBATION FOR GENERAL ANESTHESIA
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Keywords
Lidocaine, Dexamethasone, Postoperative sore throat, Endotracheal intubation.
Abstract
To compare the effectiveness of intravenous lidocaine alone versus lidocaine combined with dexamethasone in reducing the incidence of postoperative sore throat (POST) following endotracheal intubation.
Study Design: Randomized controlled trial.
Place and Duration: Department of Anesthesiology, Nishtar Medical University Multan, from 13th April 2023 to 12th October 2023.
Methodology: A total of 216 patients aged 18–60 years undergoing elective surgery under general anesthesia were enrolled. Patients were randomly allocated into two equal groups. Group L received intravenous lidocaine (1.5 mg/kg), while Group DL received intravenous lidocaine (1.5 mg/kg) plus dexamethasone (8 mg) 5 minutes prior to induction. POST was assessed within 24 hours postoperatively.
Results: The incidence of POST was significantly lower in Group DL (26.85%) compared to Group L (43.52%) (p=0.010).
Conclusion: The addition of dexamethasone to lidocaine significantly reduces the incidence of POST compared to lidocaine alone.
References
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Tayel Awan
Senior lecturer Anesthesia ,SIUT karachi
Pardeep kumar
Senior lecturer Anesthesia ,SIUT karachi
Faiza gull
Senior registrar Anesthesia, Ibn e sina hospital, Multan
Erum Naz
Consultant Anaesthesiologist ,SIUT Karachi
Tasmia Bashir
Resident Anesthesia ,SIUT Karachi
Muhammad Arif
Assistant Professor Anaesthesia , Ziauddin University Hospital
Syed Wahaj Uddin
Assistant Professor Anaesthesia , SIUT Karachi
Muhammad aatir fayyaz
Associate professor of Anesthesia , Nishtar hospital multan
