GLYCEMIC CONTROL AND ITS DETERMINANTS: AN ANALYSIS OF RISK FACTORS AND TREATMENT OUTCOMES IN DIABETES MELLITUS
Main Article Content
Keywords
Glycemic control, Diabetes mellitus, Dyslipidemia, HbA1c, Treatment outcomes
Abstract
Diabetes mellitus remains a major global health challenge, with suboptimal glycemic control contributing significantly to disease burden and complications. This study aimed to assess glycemic control and its determinants among adults with diabetes mellitus. A cross-sectional analytical approach was used, including 1,602 participants with complete glycohemoglobin (HbA1c) measurements. Glycemic control was classified as good (HbA1c <7%) or poor (HbA1c ≥7%). Descriptive statistics, chi-square tests, independent t-tests, analysis of variance, and multivariable logistic regression were performed. The prevalence of poor glycemic control was 47.88%, with a mean HbA1c of 7.40 ± 1.67%. Significant associations were observed between glycemic control and age, race/ethnicity, dyslipidemia, treatment group, and diabetes duration. Participants with poor glycemic control had higher total cholesterol, triglycerides, and longer disease duration, along with lower high-density lipoprotein levels. Treatment patterns indicated that individuals receiving insulin-based therapies had higher HbA1c levels, likely reflecting disease severity. Multivariable analysis identified dyslipidemia, age, and treatment group as independent predictors of poor glycemic control. These findings highlight the multifactorial nature of glycemic regulation and emphasize the need for integrated management strategies targeting both glycemic and metabolic risk factors. Early identification of high-risk individuals and optimization of treatment approaches are essential to improve outcomes and reduce the burden of diabetes.
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