ASSOCIATION BETWEEN SERUM 25-HYDROXYVITAMIN D LEVELS AND FREQUENCY OF EXACERBATIONS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS
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Keywords
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Abstract
Objective: To determine the association between serum 25-hydroxyvitamin D levels and frequency of acute exacerbations in patients with chronic obstructive pulmonary disease (COPD).
Methods: This analytical cross-sectional study was conducted from November 2024 to May 2025 in Doctor Hospital and Farooq Hospital Lahore. A total of 150 COPD patients aged ≥40 years were enrolled using consecutive sampling. Serum 25(OH) D levels were measured using chemiluminescent immunoassay.
Results: Vitamin D deficiency was observed in approximately60% of patients. Frequent exacerbations were significantly associated with lower serum vitamin D levels (p <.001).
Conclusion: Vitamin D deficiency is highly prevalent among COPD patients and is significantly associated with increased exacerbation frequency.
References
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Dr Noor-Ul-Arfeen
Consultant Pulmonology & Medical ICU, Doctors Hospital & Medical Centre Lahore
Dr Ali Anwar
Consultant Pulmonology & Medical ICU, Doctors Hospital & Medical Centre Lahore
Dr Usman Ahmad Kamal
Medicine, Resident Physician, Doctors Hospital & Medical Centre Lahore
Dr Faizan Ali Khan
Medical ICU, MO, Doctors Hospital & Medical Centre Lahore
Dr Muhammad Mussab Aman
Medical ICU, MO, Doctors Hospital & Medical Centre Lahore
Dr Aaiz Hassan
Pulmonology & Medical ICU, Resident Pulmonology, Doctors Hospital & Medical Centre Lahore
