ANTIBIOTIC SUSCEPTIBILITY PATTERN OF PSEUDOMONAS AERUGINOSA FROM CRITICAL AND NON-CRITICAL AREAS FROM A TERTIARY CARE HOSPITAL
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Abstract
Understanding and comparing antibiotic susceptibility patterns of P. aeruginosa isolates from critical and non-critical areas is essential for guiding empirical therapy, implementing antimicrobial stewardship programs, and strengthening infection control measures in tertiary care hospitals (6). Therefore, this study was carried out to compare the antibiotic Susceptibility Pattern of Pseudomonas aeruginosa from Critical and Non-Critical Areas from a Tertiary Care Hospital.
METHODS: This cross-sectional study was done in the Department of Microbiology, Index Medical College, Hospital and Research Centre, M.U. Indore MP. 300 samples from patients of all age group and both sexes were enrolled in the study. The isolates were identified by standard microbiological laboratory test methods. In accordance with CLSI 2025 guidelines, each isolate was subjected to an AST using the Kirby-Bauer disc diffusion method.
RESULTS:
Out of total of 300 Pseudomonas aeruginosa isolates, 42 (14%) were from critical area and 258 (86%) were from non-critical area. Pseudomonas aeruginosa from criticale area was most commonly isolated from blood (40.4%) and from non-critical area pus (46.1%) was the most common specimen. Among critical area highest isolation was from surgical ICU (47.6%). Among non-critical area highest isolation was from medicine ward (31.8%). All isolates were 100% susceptible to colistin and polymyxin B and more than 90% isolates were susceptible to imipenem and meropenem in both the areas. Ceftazidime was the least susceptible.
CONCLUSION: The prevalence and sensitivity of P. aeruginosa sometimes vary between communities, hospitals in the same community and among various patient group in the same hospital. The doctor in clinical practice must make clinical decisions in the face of these variances, and they should have access to up-to-date information on the prevalence and pattern of antibiotic resistance of frequently encountered infections.
References
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Surbhi Verma
PhD. Scholar, Department of Microbiology, Index Medical college hospital & research centre, Indore, Madhya Pradesh.
Dr Kailash Jatav
Associate professor, Department of Microbiology ,Index Medical college hospital & research centre, Indore, Madhya Pradesh.
Aneesh Sharma
PhD. Scholar, Department of Microbiology, Index Medical college hospital & research centre, Indore, Madhya Pradesh.
