Preparation and characterization of new mixed complexes of some transition elements with tyrosine and 8-hydroxyquinoline

Main Article Content

Wisam A. Abdulrahman
Nabaa Nabeel Mohammed
Menaa AbdulSalam Al-Abbasi
Marwan Q. ALSamarraie


8-Hydroxyquinoline, Biological activity, Tyrosine


A new group of metal compounds with the formula [Co (tyr & 8-H) 2 (H2O) 2] Cl2 was prepared by reacting 8-Hydroxyquinoline & Tyrosine and selected manganese (II), cobalt (II), and nickel (II) ions (II),and Cu(II). As for the compounds that were diagnosed through the UV-visible spectrophotometer, TGA, and the infrared device. These diagnoses refer to the bonding of the bi-dental metal ion via nitrogen atoms ((amide group)).

Abstract 193 | pdf Downloads 130


1. G. Sridhar., M. Bilal and D. Easwaramoorthy. Synthesis, Characterization, and Antimicrobial Activities of Copper, Nickel, Cobalt, Chromium
Complexes Derived from (Z)-4-Fluoro-N-(2,7- dimethylhept-6-enylidene) benzylamine. J. Braz.Chem. Soc. 2017, 28(5), 756-767.
2. Anurag Geete, B. D. Shrivastava and Ashutosh Mishra. XRD Study of Cobalt [Co(ii)] Complexes Synthesized with Ligands of Aniline/Toluidine Dithiocarbamate. RASAYAN J. Chem., 2020 ,13(3),1878-1884.
3. N. Jaiswal, A. Kumar Kushwah and A. Pratap. Synthesis, spectroscopic ,characterization and computational studies of Schiff base complexes
of tin(IV) chloride. Main Group Met. Chem. ,2019; 42: 28–36.
4. V. Patel, P. Trivedi, and H. Gohel. Synthesis and Characterization of Schiff Base of p - chloro aniline and their Metal Complexes and their
evaluation for Antibacterial Activity. IJAPBC, 2014, 3(4), 156-169.
5. S. Leela, T. Deepa Rani, and A. Subashini. Studies on growth and characterization of nonlinear optical material 4-chloro-40methoxy
benzylidene aniline: A Schiff base organic material. Arabian Journal of Chemistry, 2017 10, S3974–S3981.
6. B. Bahule, S. B. Kalaskar and R. P. Yadav . Synthesis, Characterisation, and Biological Study of Nickel Complexes Derived from Schiff Bases
of p-nitro Aniline and m-nitro Aniline with Aromatic Aldehydes. Int. J. Adv. Res. 2017,2(7) 5715-708.
7. A. Owolabi Sobola, G. Mostyn Watkins and B. Van Brecht. Synthesis, Characterization and Antimicrobial Activity of Copper(II) Complexes
of some Ortho-substituted Aniline Schiff Bases; Crystal Structure of Bis(2-methoxy-6-imino) methyl phenol Copper(II) Complex. S. Afr. J. Chem., 2014, 67, 45–51.
8. S. Hamza Abbas, D. Mohammad Ali and H. Hamza Abbas. Spectral and cyclic voltammetry studies of chloro-salicyliden aniline and some of
its complexes with Co(II) and Mn(II). Journal of Physics: Conference Series, 2020, 1660,1-11.
9. Enass, J. W., "Synthesis, Spectral and Thermal Characterization of Ni(II), Cu (II) and Zn(II) Complexes with New Ligand Towards Potential
Biological Application." Biochemical and Cellular Archives, 20.1 (2020): 2483-2494.
10. Ayesha Durrani1, D. D. Kayande2 and R. K. Pardeshi3. Binary complexes of N-[2-hydroxy-1- naphthalidine]-2-chloroaniline with transition
elements. J. Chem. Pharm. Res., 2015, 7(12):813- 815.
11. A. I. Fatima Al-Khodir , M. A.Hana Abumelha. New Platinum(IV) and Palladium(II) Transition Metal Complexes of s-Triazine Derivative: Synthesis, Spectral, and Anticancer Agents Studies. BioMed Research International. 2019,4, 1-14.
12. K. Rajendra Jain and A. P. Mishra. Microwave synthesis, spectral, thermal, and antimicrobial activities of some transition metal complexes involving 5-bromosalicylaldehyde moiety. Current Chemistry Letters 1. 2012, 163– 174.
13. E. Jonathan Chellali, C. Keely ,and Graham Bell. Cobalt and zinc halide complexes of 4-chloro and 4-methylaniline: Syntheses, structures, and magnetic behavior. Polyhedron, 2019,168, 1–10.
14. S. Kong, C. Guo and W. Yang .2,6- Dibenzhydryl-N-(2-phenyl imino ace naphthylenylidene)-4-chloroaniline nickel dihalides: Synthesis, characterization and ethylene polymerization for polyethylenes with high molecular weights. Journal of Organometallic Chemistry .2013, 725, 37-45.
15. M. Asma, A. Badshah, and S. Ali . Synthesis and Anti-bacterial Application of Copper (II) Salicyldehyde Schiff Base Complex. Austin J Anal Pharm Chem. 2016; 3(4): 1077-1145
16. 16- F. Mahasin Alias, N. Ameena Seewan. Synthesis, Spectral Study, Theoretical Treatment and Biological Activity of Some Transition Metal Complexes with 2-Amino Acetic Acid-6-Chloro Benzothiazole. DJPS. 2013, 9(4),93-103.
17. F. Miguel Molano, P. Vaneza Lorett and F. Mauricio. Crystal structures of organoplatinum complexes containing alkyleugenoxyacetate and
p-chloroaniline. Acta Cryst. 2016. E72, 912–917.
18. M. Molani, L. Vanezai . Crystal structure, spectroscopic characterization, and Hirshfeld surface analysis of aquadichlorido{N-[(pyridin-2-
yl)methylidene]aniline}copper(II) Monohydrate. Acta Cryst. 2020, 76(2), 48-154.
19. Sarhan, Basima M., Nada J. Kadhim, and Enas J. Wheed. "Stability constant of some Metal Ion Complexes of (6-(2Amino-2-(4-hydroxy phenyl)-acetamido)-3, 3-di methyl-7oxo-4-thia-1- aza-bicyclo [3, 2, 0] heptanes-2carboxylicacid (Amoxicillin) ." Ibn AL-Haitham Journal For
Pure and Applied Science 26.3 (2017): 245-253.
20. K. Subashini1, P. Priyadharsani, and K.Thamaraiselvi. Synthesis, growth and characterization of dichloro bis (4-chloroanilineκN)zinc semi-organic crystal. Journal of Materials Science: Materials in Electronics. 2018,29: 4147–4154.
21. M. Rani , S. Sathiya and M.Vimala. Synthesis, Characterization and Biological Activity of Transition Metal Complexes Supported. IJEAT. 2015,4(7): 2249 – 8958.
22. Enass, W. J., and Awf A.R. A. "Synthesis, Characterization, Thermal Study, Biological Activity and Corrosion Inhibition of New Ligand Derived from Butanedioyl Dichloride and Some Selective Transition Metal Complexes." Journal of Global Pharma Technology 11.2 (2019): 379- 391.
23. S. Jalal Hosseini, M. Manoochehri, and M. Daghighi Asli. Synthesis of Cobalt nanoparticles by Complex DemolitionMethod Using the Reaction between Organic Ligand Schiff base and Cobalt Chloride by Ultrasonication. Bulletin de la Société Royale des Sciences de Liège. 2017,86: 182 – 188.
24. Sarhan, Basima M., Sajid M. Lateef, and Enass J. Waheed. "Synthesis and Characterization of Some Metal Complexes of [N-(1, 5-dimethyl3-oxo-2-phenyl-2, 3-dihydro-1H-pyrazol4- ylcarbamothioyl) acetamide]." Ibn AL-Haitham Journal For Pure and Applied Science 28.2 (2017): 102-115.
25. L. Yamilka Salina-Aguilera, C. Armando Ferrer- Serrano and F. Nápoles-EscutaryI. Copper (II) and zinc (II) with 2-(4-Chloroaniline)-1,2-
Diphenyl-1-Ethano thiosemicarbazone in Solution: Possible Competition for Ligand. Coordination Sites. Revista Cubana de Química,
págs. 2014,2(5)94-103.
26. L. Nimmy John, K. Lija Joy and M. Saravana Kumar. Quantitative structure and activity relationship on the biological, nonlinear and spectroscopic properties of the Schiff base material: 4- chloro-4′bromobenzylidene aniline. Molecular Simulation, 2017,1-15.
27. Enass, J. Waheed, et al., "Synthesis And Characterization of New Manganese(II), Cobalt(II), Cadmium(II) and Mercury (II) Complexes with ligand [N-(3-acetylphenylcarbamothioyl)-2-chloroacetamide] and their Antibacterial Studies", Conf. Series: Journal of Physics 1234 (2019):1-11.
28. P. Oliver Dunstan and A. Majeed Khan. Thermochemical Parameters of 3-Chloroaniline Complexes of Certain Bivalent Transition Metal
Bromides. Open Journal of Physical Chemistry. 2013, 3, 163-169.
29. S. Park, K. Jungkyu Lee and H. Lee. Zinc (II), palladium (II) and cadmium (II) complexes containing 4‐methoxy‐N‐(pyridin‐2‐ylmethylene)
aniline derivatives: Synthesis, characterization, and methyl methacrylate polymerization. Appl Organometal Chem. 2019, 4797:1-15.
30. A. Subashini, S. Lee, and K. Ramamurthi. Synthesis, growth, and characterization of 4- bromo- 4-nitro benzylidene aniline (BNBA): a
novel nonlinear optical material with a (3+1)-dimensional incommensurately modulated structure3. CrystEngComm, 2013, 15, 2474–2481.
31.. R. Sharma, B. Reddi and S. Bhattacharya. Synthesis, crystal growth, structural and physicchemical studies of the novel binary organic complex: 4-chloroaniline–3-hydroxy-4-methoxy benzaldehyde. Journal of Solid State Chemistry. 2012,190: 226–232.
32. G. Subashini Bhagavannarayana and K. Ramamurthi.Synthesis, growth, crystalline perfection of 4-bromo-40dimethylamino benzylidene aniline (BDMABA) and photons absorption of BDMABA crystal. Molecular and Biomolecular Spectroscopy 2013,104: 403–408.
33- A.Tukur and A.Yusuf Isah. Physical Science & Biophysics Journal Committed to Create Value for Researchers Synthesis, Characterization and Antimicrobial Studies of 2-{(E)-[(4- Chlorophenyl)Imino]Methyl}Phenol Schiff Base Ligand and its Cu(II) Complex Synthesis, Characterization, and Antimicrobial Studies of 2- {(E)- [(4-Chlorophenyl)Imino]Methyl}Phenol Schiff Base Ligand and its Cu(II) Complex. Phys.
sci. 2020, 4(2): 000159:1-6.
34. A. Banan Akrawi, M. Ahlam Jameil and G. Amel Abed. Association Equilibria of Co(II) and Cu(II) Complexes of Salicylidine p-chloroaniline in Different Solvents. Sci. 2013, 24(2),55-69.