STUDY OF FACTORS ASSOCIATED WITH ANTI-RABIES POST EXPOSURE PROPHYLAXIS COMPLIANCE AMONG ANIMAL BITE CASES ATTENDING REFERRAL CENTRES OF VIDISHA, MADHYA PRADESH
Main Article Content
Keywords
Compliance, Rabies, Anti Rabies Vaccine, Rabies Immunoglobulin, Post Exposure Prophylaxis
Abstract
Introduction: Rabies is a viral infection of the neurological system that is spread by the bite of rabid animals such as dogs, rats, cats, bats, raccoons, and foxes. It is also one of the deadliest viruses, with a near 100% case‑fatality rate once symptoms appear.
Aim: To assess the compliance of Anti Rabies Vaccine and Rabies immunoglobulin (RIG) among the animal bite patients.
Objectives: 1. To Determine the Socio-demographic characteristics of patients attending Rabies clinic 2. To identify the factors that influence compliance with Anti Rabies Vaccine and Rabies immunoglobulin among the animal bite patients 3. To identify the proportion of animal bite patients receiving the PEP of Rabies according to the Schedule.
Methodology: Patients on their first visit were interviewed and followed up until their last scheduled date of receiving ARV. During their interview, patients were asked how many days after the dog bite they came for vaccination. Patients who came for their scheduled dose were checked to see if they arrived on the scheduled day.
Results: Out Of the 386 study participants, 198 (51.29%) were found to be compliant to the full course of ARV, 158 (40.94%) were found to be noncompliant, and 30 (7.77%) cases were of delayed compliance. Key determinants of non-compliance identified in this study were distance from healthcare facilities (47.66%), fear of wage loss (28.03%), and forgetfulness (22.43%)
Conclusion: In the current study, it was observed that 51.29% were compliant to the full course of ARV. Key determinants of non-compliance identified in this study were modifiable barriers that can be addressed through targeted interventions. Wound management practices revealed significant gaps. This represents a critical missed opportunity for primary prevention of rabies infection.
References
2. BanyardAC, Tordo N. Rabies pathogenesis and immunology. Rev Sci Tech 2018;37:323 30.
3. Rabies. Available from: https://www.who.int/news room/fact sheets/detail/ rabies. [Last accessed on 2024 February 17].
4. Rabies – India. Available from: https://www.who.int/westernpacific/ health topics/rabies. [Last accessed on 2024 February 17]
5. Sahu D P, Ps P, Bhatia V, et al. (March 31, 2021) Anti-Rabies Vaccine Compliance and Knowledge of Community Health Worker Regarding Animal Bite Management in Rural Area of Eastern India. Cureus 13(3): e14229. DOI 10.7759/cureus.14229
6. Shivasakthimani R, Vinoth GCD, Ravivarman G, Murali R. Compliance of antirabies vaccine among dog bite victims in an urban slum of Chennai: a cross sectional study. Int J Community Med Public Health 2018;5:1487-91.
7. Matibag GC, Ohbayashi Y, Kanda K, Yamashina H, Kumara WR, Perera IN, et al. A pilot study on the usefulness of information and education campaign materials in enhancing the knowledge, attitude and practice on rabies in rural Sri Lanka. J Infect Dev Ctries 2009;3:55 64.
8. Domple V, Doibale M, Sonkar V, Aswar N, Khadilkar H, Jain S. Treatment compliance of selfreported dog bite cases attending outpatient department of Tertiary Care Hospital, Maharashtra. Int J Med Public Health. 2015;5(4):297.
9. Sundaram P, Ravishankar M, Ponniah M, Kadal KK, Palani D. Compliance of Post-Exposure Prophylaxis of Anti-rabies Vaccine amongst Animal Bite Cases Attending Secondary Healthcare Hospital in Thiruvallur District, Tamil Nadu, India: A Cross-sectional Study. J Clin Diagn Res. 2024;185 FC01FC04.
10. Sharma R, Gupta A, Sharma V. Compliance to post-exposure prophylaxis among patients attending anti-rabies vaccination clinic in a tertiary health care centre in central India: a cross sectional study. Int J Community Med Public Health. 2023;108 28902896.
11. Mahajan V, Kashyap B, Praveen G, Subhashini KJ, Metri SS, Sundar M. Assessment of compliance to anti-rabies vaccination among animal bite victims attending anti-rabies clinic of a tertiary care hospital, Hassan, Karnataka. MedPulse Int J Community Med. 2019;113 2631.
12. Singh V, Gupta S, Agarwal GP. Compliance to rabies immunoglobulin in post-exposure prophylaxis of category III animal bite cases attending antirabies clinic of government tertiary care hospital, Solapur. Int J Community Med Public Health. 2016;311 31663169.
13. Patil S, Yerpude P, Jogdand K, Khed K. Compliance to anti rabies vaccine and animal bite management practices in a rural area of Davangere, Karnataka, India. Int J Community Med Public Health. 2017;31 170173.
14. Kumar A, Singh OP, Chaudhary A. A study of compliance of animal bite victims to 4 dose intradermal schedule of anti-rabies vaccine and factors affecting it. Int J Community Med Public Health. 2017;22 156161

