EFFICACY OF PROPHYLACTIC INTRAVENOUS DEXAMETHASONE FOR PREVENTION OF POST‑SPINAL ANAESTHESIA SHIVERING IN PATIENTS UNDERGOING TRANSURETHRAL RESECTION OF THE PROSTATE UNDER SPINAL ANAESTHESIA
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Abstract
Methods: A prospective, randomised, double-blind, placebo-controlled trial was conducted at the Sindh Institute of Urology and Transplantation. Sixty patients scheduled for elective TURP under spinal anaesthesia were randomly allocated to receive either dexamethasone 0.1 mg/kg or normal saline (placebo) 30 minutes before spinal anaesthesia. Shivering was assessed using the Wrench scale at predefined intervals. Axillary temperature and postoperative nausea and vomiting (PONV) were also recorded.
Results: Intraoperative shivering occurred in 100% of the dexamethasone group and 96.8% of the placebo group (P=1.000). High-grade shivering was comparable between groups (75.8% vs 74.2%). Postoperative shivering rates were similar (27.3% vs 29.0%; P=1.000), though resolution time tended to be shorter in the dexamethasone group (16.7 ± 8.0 vs 25.2 ± 11.1 minutes; P=0.081). No significant differences were observed in temperature trends or PONV incidence.
Conclusion: Prophylactic dexamethasone (0.1 mg/kg) did not significantly reduce the incidence or severity of intraoperative shivering in elderly TURP patients under spinal anaesthesia.
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Dr. Rameez Ali
Senior Lecturer, Department of Anaesthesia, SIUT, Karachi, Pakistan [email protected]
Muhammad Siddique
2Associate professor, Anesthesia SIUT
Hiranand
Assistant professor Anesthesia SIUT
Mansoor Chandio
Assistant professor Anesthesia SIUT
Dr Zamir Ahmad
Professor of Anesthesia Anesthesia SIUT
Qamar Abbas
Professor of Anesthesia Anesthesia SIUT
