BIOSENSORS IN VARIOUS FOOD APPLICATIONS- A SYSTEMATIC REVIEW
Main Article Content
Keywords
Biosensors, Food, spoilage, microbial, analyte.
Abstract
Biosensors are replacing the traditional quality checking and safety measure methods in food industry. Their robust applications in various sectors, specifically in food sector have been an advantage in supplying fresh food from farm to fork. These increased the food supply chain business to mitigate export needs and have shown proven results by detecting food borne pathogens and other contaminants during storage, processing until it reaches consumer. Combining the sensor technology to biological molecules detection has great importance in assessment of authenticity of foods in the adulteration market. An attempt was made to construct a systematic review on biosensors in various food applications which might throw light in understanding and developing specific methods for rapid quality assurance of food until it reaches the consumer.
References
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30. Raza, W., Ahmad, K., & Oh, T. H. (2025). Progress in Layered Double Hydroxide-Based Materials for Gas and Electrochemical Sensing Applications. Chemosensors, 13(3), 115.
31. Rodriguez-Herrera, J., Cabado, A. G., Bodelón, G., Cunha, S. C., Pinto, V., Fernandes, J. O., ... & Minas, G. (2021). Methodological approaches for monitoring five major food safety hazards affecting food production in the Galicia–Northern Portugal Euroregion. Foods, 11(1), 84.
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33. Sharma, R., Verma, A., Shinde, N., Mann, B., Gandhi, K., Wichers, J. H., & van Amerongen, A. (2021). Adulteration of cow’s milk with buffalo’s milk detected by an on-site carbon nanoparticles-based lateral flow immunoassay. Food Chemistry, 351, 129311.
34. Sharma, V. K., Sharma, M., Usmani, Z., Pandey, A., Singh, B. N., Tabatabaei, M., & Gupta, V. K. (2022). Tailored enzymes as next-generation food-packaging tools. Trends in Biotechnology, 40(8), 1004-1017.
35. Sreeram, A., & Kathirvelan, J. (2024). Design and development of ethylene gas sensor for non-destructive analysis of food quality: an updated review. Sensor Review, 44(3), 267-283.
36. Vargas-Bernal, R., Rodríguez-Miranda, E., & Herrera-Pérez, G. (2012). Evolution and expectations of enzymatic biosensors for pesticides. Pesticides-Advances in Chemical and Botanical Pesticides, 14, 331-354.
37. Vasconcelos, H., Coelho, L. C., Matias, A., Saraiva, C., Jorge, P. A., & de Almeida, J. M. (2021). Biosensors for biogenic amines: A review. Biosensors, 11(3), 82.
38. Wang, C., Xiao, R., Wang, S., Yang, X., Bai, Z., Li, X., ... & Wang, S. (2019). Magnetic quantum dot based lateral flow assay biosensor for multiplex and sensitive detection of protein toxins in food samples. Biosensors and Bioelectronics, 146, 111754.
39. Wang, H., Sun, Z., Qi, Y., Hu, Y., Ni, Z., & Li, C. (2024). Update application of enzyme in food processing, preservation, and detection. Food Bioengineering, 3(3), 380-394.
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41. Wang, S., Wang, H., Ding, Y., Li, W., Gao, H., Ding, Z., ... & Ye, J. (2022). Filter paper-and smartphone-based point-of-care tests for rapid and reliable detection of artificial food colorants. Microchemical Journal, 183, 108088.
42. Wu, Z., Hao, Z., Chai, Y., Li, A., Wang, C., Zhang, X., ... & Lu, C. (2023). Near-infrared-excitable acetylcholinesterase-activated fluorescent probe for sensitive and anti-interference detection of pesticides in colored food. Biosensors and Bioelectronics, 233, 115341.
43. Xu, W., Chen, L., Hu, X., Zhang, L., Huang, D., Li, J., ... & Zhu, M. (2024). Botanic signal monitor: advanced wearable sensor for plant health analysis. Advanced Functional Materials, 34(51), 2410544.
44. Ye, S., Duan, J., Yuan, J., Liu, G., Lin, J., & Wang, Y. (2025). Development of a portable dropper-based biosensor for rapid and cost-effective detection of Salmonella typhimurium in food samples. Analytica Chimica Acta, 344735.
45. Yu, D., Cheng, S., Li, Y., Su, W., & Tan, M. (2024). Recent advances on natural colorants-based intelligent colorimetric food freshness indicators: fabrication, multifunctional applications and optimization strategies. Critical Reviews in Food Science and Nutrition, 64(33), 12448-12472.
46. Zhang J, Huang H, Song G, Huang K, Luo Y, et al. 2022. Intelligent biosensing strategies for rapid detection in food safety: a review. Biosens Bioelectron 202: 114003. https://doi.org/10.1016/j.bios.2022.114003
47. Zhang, W., Sun, D. W., Ma, J., Wang, Z., Qin, A., & Tang, B. Z. (2023). Simultaneous sensing of ammonia and temperatures using a dual-mode freshness indicator based on Au/Cu nanoclusters for packaged seafood. Food Chemistry, 418, 135929.
48. Zhang, X., Zhao, J., Wang, C., Zhu, L., Pan, X., Liu, Y., ... & Chen, D. (2023). Measurement of sucrose in beverages using a blood glucose meter with cascade-catalysis enzyme particle. Food Chemistry, 398, 133951.
49. Zhao, X., Bhat, A., O’Connor, C., Curtin, J., Singh, B., & Tian, F. (2024). Review of detection limits for various techniques for bacterial detection in food samples. Nanomaterials, 14(10), 855.
50. Zheng, L., Jiang, Y., Huang, F., Wu, Q., & Lou, Y. (2023). A colorimetric, photothermal, and fluorescent triple-mode CRISPR/cas biosensor for drug-resistance bacteria detection. Journal of Nanobiotechnology, 21(1), 493.
51. Zhou J, Lv X, Jia J, Din ZU, Cai S, et al. 2022. Nanomaterials-based electrochemiluminescence biosensors for food analysis: recent devel¬opments and future directions. Biosensors 12(11): 1046. https://doi. org/10.3390/bios12111046
2. Aslan, N., Akan, M., Kanbes-Dindar, C., & Uslu, B. (2025). Applications of Sensors in Food Quality Control. In Handbook of Carbon Sensors (pp. 172-203). CRC Press.
3. Bharathi, S. K. V., Sukitha, A., Moses, J. A., & Anandharamakrishnan, C. (2018). Instrument-based detection methods for adulteration in spice and spice products-a review.
4. Bhat, G. P., Shrikrishna, N. S., Kumari, M., & Gandhi, S. (2025). Electrochemical Biosensing of Organophosphates. In Agricultural Electrochemistry (pp. 227-253). American Chemical Society.
5. Bodkhe, G. A., Kumar, V., Li, X., Pei, S., Ma, L., & Kim, M. (2025). Biosensors in Microbial Ecology: Revolutionizing Food Safety and Quality. Microorganisms, 13(7), 1706.
6. Campas, M., Leonardo, S., Ferre-Gode, A., Chowdhury, A. A., Toldra, A., Andree, K. B., & Roque, A. (2023). Duplex electrochemical biosensor for the detection of the tdh and trh virulence genes of Vibrio parahaemolyticus in oysters. Food Control, 149, 109689.
7. Campuzano, S., Barderas, R., Moreno-Casbas, M. T., Almeida, Á., & Pingarrón, J. M. (2024). Pursuing precision in medicine and nutrition: the rise of electrochemical biosensing at the molecular level. Analytical and Bioanalytical Chemistry, 416(9), 2151-2172.
8. Carducci, N. G. G., Dey, S., & Hickey, D. P. (2024). Recent Developments and Applications of Microbial Electrochemical Biosensors. Trends in Biosensing Research: Advances, Challenges and Applications, 149-183.
9. Chen, Z., Liu, Z., Liu, J., & Xiao, X. (2023). Research progress in the detection of common foodborne hazardous substances based on functional nucleic acids biosensors. Biotechnology and Bioengineering, 120(12), 3501-3517.
10. Cossettini, A., Vidic, J., Maifreni, M., Marino, M., Pinamonti, D., & Manzano, M. (2022). Rapid detection of Listeria monocytogenes, Salmonella, Campylobacter spp., and Escherichia coli in food using biosensors. Food Control, 137, 108962.
11. Eyvazi, S., Baradaran, B., Mokhtarzadeh, A., & de la Guardia, M. (2021). Recent advances on development of portable biosensors for monitoring of biological contaminants in foods. Trends in Food Science & Technology, 114, 712-721.
12. Fernandez Abedul, M. T., González García, M. B., & Costa García, A. (2015). Electrochemical immunosensors. Agricultural and Food Electroanalysis, 223-93.
13. Gao, S., Hao, J., Su, D., Wu, T., Gao, J., & Hu, G. (2021). Facile and sensitive detection of norfloxacin in animal-derived foods using immuno-personal glucose meter. European Food Research and Technology, 247(10), 2635-2644.
14. González-Pereira, A., Otero, P., Fraga-Corral, M., Garcia-Oliveira, P., Carpena, M., Prieto, M. A., & Simal-Gandara, J. (2021). State-of-the-art of analytical techniques to determine food fraud in olive oils. Foods, 10(3), 484.
15. Huang, Y., Su, Z., Li, W., & Ren, J. (2022). Recent progresses on biosensors for Escherichia coli detection. Food Analytical Methods, 15(2), 338-366.
16. Janssen, S., Schmitt, K., Blanke, M., Bauersfeld, M. L., Wöllenstein, J., & Lang, W. (2014). Ethylene detection in fruit supply chains. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 372(2017), 20130311.
17. Kalaitzis, P., & El‐Zein, Z. (2016). Olive oil authentication, traceability and adulteration detection using DNA‐based approaches. Lipid Technology, 28(10-11), 173-176.
18. Kaur, G., Panigrahi, C., & Agrawal, S. (2024). Role of Nanotechnology in Detection of Heavy Metals in Food Products. In Nanotechnology in the Food Industry (pp. 157-182). CRC Press.
19. Kundu, M., & Ghosh, S. (2024). Sensing food quality by silicene nanosheets: a Density Functional Theory study. arXiv preprint arXiv:2406.07205.
20. Lee, J. M., Lee, Y., Devaraj, V., Nguyen, T. M., Kim, Y. J., Kim, Y. H., ... & Oh, J. W. (2021). Investigation of colorimetric biosensor array based on programable surface chemistry of M13 bacteriophage towards artificial nose for volatile organic compound detection: From basic properties of the biosensor to practical application. Biosensors and Bioelectronics, 188, 113339.
21. Liu, S., Zhao, K., Huang, M., Zeng, M., Deng, Y., Li, S., ... & Chen, Z. (2022). Research progress on detection techniques for point-of-care testing of foodborne pathogens. Frontiers in Bioengineering and Biotechnology, 10, 958134.
22. Mani, R., Kumar, J. V., Murugesan, B., Alaguthevar, R., & Rhim, J. W. (2025). Smart Sensors in Food Packaging: Sensor Technology for Real‐Time Food Safety and Quality Monitoring. Journal of Food Process Engineering, 48(4), e70120.
23. Manzano, M., Viezzi, S., Mazerat, S., Marks, R. S., & Vidic, J. (2018). Rapid and label-free electrochemical DNA biosensor for detecting hepatitis A virus. Biosensors and Bioelectronics, 100, 89-95.
24. Mishra, P., Lee, J., Kumar, D., Louro, R. O., Costa, N., Pathania, D., ... & Singh, L. (2022). Engineered nanoenzymes with multifunctional properties for next‐generation biological and environmental applications. Advanced Functional Materials, 32(8), 2108650.
25. Nehal, N., Choudhary, B., Nagpure, A., & Gupta, R. K. (2021). DNA barcoding: A modern age tool for detection of adulteration in food. Critical reviews in biotechnology, 41(5), 767-791.
26. Niu, H., Zhang, M., Shen, D., Mujumdar, A. S., & Ma, Y. (2024). Sensing materials for fresh food quality deterioration measurement: a review of research progress and application in supply chain. Critical reviews in food science and nutrition, 64(22), 8114-8132.
27. Raj, P., Oh, M. H., Han, K., & Lee, T. Y. (2021). Label-free electrochemical biosensor based on Au@ MoS₂–PANI for Escherichia coli detection. Chemosensors, 9(3), 49.
28. Rakha, A., Arshad, R., Basit, R. A., Toor, A., Afzal, M., & Tahir, H. E. (2024). Application of colorimetric sensors in cereal and cereal-based foods analysis. In Colorimetric Sensors (pp. 187-211). Academic Press.
29. Ravindran, N., Kumar, S., M, Y., S, R., CA, M., Thirunavookarasu S, N., & CK, S. (2023). Recent advances in Surface Plasmon Resonance (SPR) biosensors for food analysis: A review. Critical Reviews in Food Science and Nutrition, 63(8), 1055-1077.
30. Raza, W., Ahmad, K., & Oh, T. H. (2025). Progress in Layered Double Hydroxide-Based Materials for Gas and Electrochemical Sensing Applications. Chemosensors, 13(3), 115.
31. Rodriguez-Herrera, J., Cabado, A. G., Bodelón, G., Cunha, S. C., Pinto, V., Fernandes, J. O., ... & Minas, G. (2021). Methodological approaches for monitoring five major food safety hazards affecting food production in the Galicia–Northern Portugal Euroregion. Foods, 11(1), 84.
32. Saini, R. V., Vaid, P., Saini, N. K., Siwal, S. S., Gupta, V. K., Thakur, V. K., & Saini, A. K. (2021). Recent advancements in the technologies detecting food spoiling agents. Journal of functional biomaterials, 12(4), 67.
33. Sharma, R., Verma, A., Shinde, N., Mann, B., Gandhi, K., Wichers, J. H., & van Amerongen, A. (2021). Adulteration of cow’s milk with buffalo’s milk detected by an on-site carbon nanoparticles-based lateral flow immunoassay. Food Chemistry, 351, 129311.
34. Sharma, V. K., Sharma, M., Usmani, Z., Pandey, A., Singh, B. N., Tabatabaei, M., & Gupta, V. K. (2022). Tailored enzymes as next-generation food-packaging tools. Trends in Biotechnology, 40(8), 1004-1017.
35. Sreeram, A., & Kathirvelan, J. (2024). Design and development of ethylene gas sensor for non-destructive analysis of food quality: an updated review. Sensor Review, 44(3), 267-283.
36. Vargas-Bernal, R., Rodríguez-Miranda, E., & Herrera-Pérez, G. (2012). Evolution and expectations of enzymatic biosensors for pesticides. Pesticides-Advances in Chemical and Botanical Pesticides, 14, 331-354.
37. Vasconcelos, H., Coelho, L. C., Matias, A., Saraiva, C., Jorge, P. A., & de Almeida, J. M. (2021). Biosensors for biogenic amines: A review. Biosensors, 11(3), 82.
38. Wang, C., Xiao, R., Wang, S., Yang, X., Bai, Z., Li, X., ... & Wang, S. (2019). Magnetic quantum dot based lateral flow assay biosensor for multiplex and sensitive detection of protein toxins in food samples. Biosensors and Bioelectronics, 146, 111754.
39. Wang, H., Sun, Z., Qi, Y., Hu, Y., Ni, Z., & Li, C. (2024). Update application of enzyme in food processing, preservation, and detection. Food Bioengineering, 3(3), 380-394.
40. Wang, J. J., Zhang, X. Y., Hua, M. F., Li, S. L., Wei, J., Chen, Q. M., ... & Chen, X. M. (2025). Spatially Resolved Electrochemiluminescent Biosensor Combined with Nanopore Screening Devices for Simultaneous Determination of Deoxynivalenol and Aflatoxin B1. Analytical Chemistry, 97(12), 6788-6795.
41. Wang, S., Wang, H., Ding, Y., Li, W., Gao, H., Ding, Z., ... & Ye, J. (2022). Filter paper-and smartphone-based point-of-care tests for rapid and reliable detection of artificial food colorants. Microchemical Journal, 183, 108088.
42. Wu, Z., Hao, Z., Chai, Y., Li, A., Wang, C., Zhang, X., ... & Lu, C. (2023). Near-infrared-excitable acetylcholinesterase-activated fluorescent probe for sensitive and anti-interference detection of pesticides in colored food. Biosensors and Bioelectronics, 233, 115341.
43. Xu, W., Chen, L., Hu, X., Zhang, L., Huang, D., Li, J., ... & Zhu, M. (2024). Botanic signal monitor: advanced wearable sensor for plant health analysis. Advanced Functional Materials, 34(51), 2410544.
44. Ye, S., Duan, J., Yuan, J., Liu, G., Lin, J., & Wang, Y. (2025). Development of a portable dropper-based biosensor for rapid and cost-effective detection of Salmonella typhimurium in food samples. Analytica Chimica Acta, 344735.
45. Yu, D., Cheng, S., Li, Y., Su, W., & Tan, M. (2024). Recent advances on natural colorants-based intelligent colorimetric food freshness indicators: fabrication, multifunctional applications and optimization strategies. Critical Reviews in Food Science and Nutrition, 64(33), 12448-12472.
46. Zhang J, Huang H, Song G, Huang K, Luo Y, et al. 2022. Intelligent biosensing strategies for rapid detection in food safety: a review. Biosens Bioelectron 202: 114003. https://doi.org/10.1016/j.bios.2022.114003
47. Zhang, W., Sun, D. W., Ma, J., Wang, Z., Qin, A., & Tang, B. Z. (2023). Simultaneous sensing of ammonia and temperatures using a dual-mode freshness indicator based on Au/Cu nanoclusters for packaged seafood. Food Chemistry, 418, 135929.
48. Zhang, X., Zhao, J., Wang, C., Zhu, L., Pan, X., Liu, Y., ... & Chen, D. (2023). Measurement of sucrose in beverages using a blood glucose meter with cascade-catalysis enzyme particle. Food Chemistry, 398, 133951.
49. Zhao, X., Bhat, A., O’Connor, C., Curtin, J., Singh, B., & Tian, F. (2024). Review of detection limits for various techniques for bacterial detection in food samples. Nanomaterials, 14(10), 855.
50. Zheng, L., Jiang, Y., Huang, F., Wu, Q., & Lou, Y. (2023). A colorimetric, photothermal, and fluorescent triple-mode CRISPR/cas biosensor for drug-resistance bacteria detection. Journal of Nanobiotechnology, 21(1), 493.
51. Zhou J, Lv X, Jia J, Din ZU, Cai S, et al. 2022. Nanomaterials-based electrochemiluminescence biosensors for food analysis: recent devel¬opments and future directions. Biosensors 12(11): 1046. https://doi. org/10.3390/bios12111046
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Jan 12, 2026
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Kiran Kumari Palety, Chedubavi Vinay Kumar, Chenannagaari Dheeksha, Vijaya Lakshmi Kandregula, Suneel Pappala, Pavan Kumar Gade, & Bramarambica K. (2026). BIOSENSORS IN VARIOUS FOOD APPLICATIONS- A SYSTEMATIC REVIEW. Journal of Population Therapeutics and Clinical Pharmacology, 33(1), 101-109. https://doi.org/10.53555/rbmwjd59
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Author Biographies
Kiran Kumari Palety
Department of Food Technology and Management, Loyola Academy, Secundrabad -500010 Telangana, India.
Chedubavi Vinay Kumar
Department of Food Technology and Management, Loyola Academy, Secundrabad -500010 Telangana, India.
Chenannagaari Dheeksha
Department of Food Technology and Management, Loyola Academy, Secundrabad -500010 Telangana, India.
Vijaya Lakshmi Kandregula
Gazette notifies FSSAI Food Analyst, India.
Suneel Pappala
Department of AI & DS, St.Mary’s Group of Institutions, Yadagiri Bhungiri district-508284 Telangana, India.
Pavan Kumar Gade
Department of Biotechnology, Kavitha Degree College, Khammam- 507002, Telangana, India.
Bramarambica K
R & D, Lalata Technologies (www.lalatatechnologies.com), Telangana, India.
How to Cite
Kiran Kumari Palety, Chedubavi Vinay Kumar, Chenannagaari Dheeksha, Vijaya Lakshmi Kandregula, Suneel Pappala, Pavan Kumar Gade, & Bramarambica K. (2026). BIOSENSORS IN VARIOUS FOOD APPLICATIONS- A SYSTEMATIC REVIEW. Journal of Population Therapeutics and Clinical Pharmacology, 33(1), 101-109. https://doi.org/10.53555/rbmwjd59
