“URINARY TRACT INFECTION RATES AMONG PATIENTS WITH COMPLEX KIDNEY STONES”
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Keywords
Kidney stones, urinary tract infection, PCNL, E. coli, infection control, Institute of Kidney Diseases Hayatabad Peshawar, KPK, Pakistan
Abstract
: Urinary tract infections (UTIs) are common postoperative complications in patients with complex kidney stones undergoing percutaneous nephrolithotomy (PCNL). Despite advancements in surgical techniques, infection control remains a significant challenge, particularly in high-risk populations.
Objective: To determine the prevalence, causative organisms, and associated risk factors of UTIs among patients with complex kidney stones treated at the Institute of Kidney Diseases Hayatabad Peshawar, KPK, Pakistan.
Methods: This cross-sectional study was conducted at Institute of Kidney Diseases Hayatabad Peshawar, KPK in the duration from February 2025 to July 2025, involving 180 patients with complex renal calculi who underwent PCNL. Preoperative and postoperative urine cultures were obtained. Demographic, clinical, and microbiological data were analyzed using SPSS version 26. Chi-square and logistic regression tests were Institute of Kidney Diseases Hayatabad Peshawar, KPK.
Results: Among 180 patients, 51 (28.3%) developed postoperative UTIs. The infection rate was significantly higher in females (38.9%) than males (21.3%) (p = 0.02). Escherichia coli (47%) was the most common pathogen, followed by Klebsiella pneumoniae (23%) and Pseudomonas aeruginosa (15%). High antibiotic resistance was noted against fluoroquinolones (68%) and cephalosporins (62%). Larger stone size (>2 cm) and prolonged operative time (>90 minutes) were significantly associated with infection (p < 0.05).
Conclusion: UTIs remain prevalent among patients with complex kidney stones after PCNL at Institute of Kidney Diseases Hayatabad Peshawar, KPK. Female gender, stone complexity, and extended operative duration are major predictors. Strengthened infection control measures, antibiotic stewardship, and early microbiological screening are essential to reduce postoperative complications and enhance patient outcomes.
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Dr Naseeb Dad
Consultant Urologist, Institute of Kidney Diseases Hayatabad Peshawar, KPK
Dr Mohib Ullah
Post Graduate Resident, Department of Urology, Pakistan Institute of Medical Sciences Islamabad
Dr Shakeel Haseeb Uddin Siddique
Assistant Professor of Urology, Hamdard University, Karachi, Pakistan
Dr Muzzamil Riaz Malik
Assistant Professor Nephrology, Head, Department of Nephrology, Rai Foundation Medical College Sargodha, Punjab
Dr Muhammad Waqas
Assistant Professor Urology, Mayo Hospital, King Edward Medical University, Lahore, Punjab
Dr Abdullah
Associate Professor, Urology Department, P.O.F Hospital Wah Cantt, Punjab