EVALUATION OF NEUTROPHIL TO LYMPHOCYTE RATIO AND PLATELET TO LYMPHOCYTE RATIO AMONG HYPERTENSIVE AND NORMOTENSIVE.
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Keywords
keywords use in this research are Hypertension, Neutrophil, Lymphocyte, Ratio, Platelet, Inflammation, Cardiovascular Risk, and Biomarkers
Abstract
Background: Hypertension is a major global health burden associated with chronic low-grade inflammation and elevated cardiovascular risk.
Objective: Thisstudy aimed to evaluate and compare the NLR and PLR among hypertensive and normotensive individuals and to assess the potential of these biomarkers in identifying inflammation-related risk in hypertension.
Methods: The study enrolled adult participants aged 35–65 years, classified into hypertensive and normotensive groups based on standard blood pressure criteria. Complete blood counts were analyzed to compare NLR and PLR. Statistical comparisons between groups and correlation analyses were conducted to determine the significance of these ratios.
Results: Both NLR and PLR were found to be elevated in hypertensive individuals compared to normotensive controls. The increase in NLR was statistically significant, indicating a heightened inflammatory state in hypertensive patients. Although PLR was also higher, its statistical significance varied across individuals.
Conclusion: The research concludes that both NLR and PLR were high in hypertensive individuals them that of Normotensive individual and can serve as simple, non-invasive, and effective indicators of systemic inflammation and cardiovascular risk.
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Jenkins Zehpeh
M.Sc. II Year, Department of Physiology, School of Medical Sciences and Research, Sharda University, Greater Noida, U.P., India.
Hamidou Zorome
M.Sc. II Year, Department of Physiology, School of Medical Sciences and Research, Sharda University, Greater Noida, U.P., India
Shalini Rastogi
Professor, Department of Physiology, School of Medical Sciences and Research, Sharda University, Greater Noida, U.P., India.
Rachna Rohatgi
Professor, Department of Anatomy, School of Medical Sciences and Research, Sharda University, Greater Noida, U.P., India.
Nirupma Gupta
Professor& Dean, School of Medical Sciences and Research, Sharda University, Greater Noida, U.P., India.
Sonal Rastogi
MDS Final year, Peadodontics, School of Dental sciences, Sharda University.
Vichal Rastogi
Professor, Microbiology National Capital Region Institute of Medical Sciences, Meerut,U.P.