INVESTIGATING THE ROLE OF KISSPEPTIN IN BREAST CANCER: A STUDY ON KISSPEPTIN LEVELS AND THEIR CLINICAL SIGNIFICANCE

Dr.S.Jagatheesan; Swedha.A; Vinothini. V; Rahul. F; Pavithra. G

doi:10.53555/3mz9km28

Dr.S.Jagatheesan
Swedha.A
Vinothini. V
Rahul. F
Pavithra. G

Keywords

Breast cancer, Kisspeptin, ELISA, Blood sample, Prognostic biomarker

Abstract

Background

Breast cancer remains a significant global health concern, necessitating continued research to uncover its molecular mechanisms and identify novel therapeutic targets. Kisspeptin, a peptide originally recognized for its role in reproductive physiology, has recently gained attention for its potential involvement in cancer progression. This study investigates the clinical significance of kisspeptin levels in breast cancer patients.

Methods

A total of 100 breast cancer patients were enrolled in the study. Blood samples were collected, and kisspeptin levels were quantified using Enzyme-Linked Immunosorbent Assay (ELISA). Associations between kisspeptin levels and clinicopathological parameters—including tumor stage, histological grade, hormone receptor status, and patient outcomes—were analyzed.

Results

Preliminary analysis revealed significant correlations between kisspeptin levels and key clinical parameters. Higher or lower kisspeptin expression was observed in relation to tumor progression and hormone receptor status (specific statistical outcomes to be included as available). These findings suggest a potential prognostic value of kisspeptin in breast cancer.

Conclusion

Kisspeptin shows promise as a prognostic biomarker and potential therapeutic target in breast cancer management. Understanding its role in breast cancer pathogenesis could enhance personalized treatment strategies. Further studies are needed to validate these findings and clarify the mechanistic role of kisspeptin in breast cancer.

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References

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Published

Nov 03, 2025

DOI: https://doi.org/10.53555/3mz9km28

How to Cite

Dr.S.Jagatheesan, Swedha.A, Vinothini. V, Rahul. F, & Pavithra. G. (2025). INVESTIGATING THE ROLE OF KISSPEPTIN IN BREAST CANCER: A STUDY ON KISSPEPTIN LEVELS AND THEIR CLINICAL SIGNIFICANCE. Journal of Population Therapeutics and Clinical Pharmacology, 32(10), 08-12. https://doi.org/10.53555/3mz9km28

Issue

Vol. 32 No. 10 (2025): JPTCP

Section

Articles

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