EFFECT OF MYOPIA ON THE THICKNESS OF THE RETINAL NERVE FIBRE LAYER MEASURED BY OPTICAL COHERENCE TOMOGRAPHY
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Keywords
Myopia, Retinal Nerve Fibre Layer (RNFL), Optical Coherence Tomography (OCT), Axial Length
Abstract
Background: Myopia is a refractive error where light rays focus in front of the retina. Studies using Optical Coherence Tomography (OCT) have shown temporal displacement and thinning of the retinal nerve fibre layer (RNFL) in myopia.Objectives: To evaluate the effect of myopia on the RNFL thickness measured by Optical Coherence Tomography (OCT).Methods: This observational study included 300 patients, aged 19-37 years, randomly selected from the OPD of the Department of Ophthalmology at SKIMS Medical College, Srinagar. Spectral domain OCT (Cirrus HD-OCT) was used to measure RNFL thickness in four quadrants (superior, inferior, temporal, and nasal). RNFL thickness was compared among groups with low, moderate, and high myopia.Results: The mean RNFL thickness in the temporal quadrant was correlated with the severity of myopia, showing a decrease in high myopic patients compared to moderate and low myopia. In the superior quadrant, RNFL thickness was also significantly reduced in high myopia. The average RNFL thickness showed minimal variation with age (p = 0.873). Axial length increased with the severity of myopia, with mean values of 22.7 ± 1.59 mm in Group 1 (low myopia), 23.8 ± 1.62 mm in Group 2 (moderate myopia), and 26.2 ± 2.23 mm in Group 3 (high myopia), with a statistically significant association.Conclusion: RNFL thickness decreases with increasing myopia, particularly in the superior, inferior, and nasal quadrants. Increased axial length is associated with greater myopia severity.
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Dr. Younis Ahmad Dar
Postgraduate scholar, Department of Ophthalmology, SKIMS Medical College, Bemina Srinagar, Jammu and Kashmir, India
Dr. Sheikh Sajjad
Professor and Head, Department of Ophthalmology, SKIMS Medical College, Bemina Srinagar, Jammu and Kashmir, India
Dr. Sadiya Aijaz
Postgraduate scholar, Department of Ophthalmology, SKIMS Medical College, Bemina Srinagar, Jammu and Kashmir, India
Dr. Ashaq
Postgraduate scholar, Department of Ophthalmology, SKIMS Medical College, Bemina Srinagar, Jammu and Kashmir, India