RETROSPECTIVE STUDY OF MATERNAL HYPERTENSIVE DISORDERS AND INCIDENCE OF ACUTE VESTIBULAR SYMPTOMS DURING PREGNANCY AT SHRI GURU RAM RAI INSTITUTE OF MEDICAL & HEALTH SCIENCES, DEHRADUN

Main Article Content

Dr. Patel Mehulbhai Ishverbhai
Dr. Patel Hetna Amrutlal

Keywords

acute vestibular symptoms , Hypertensive disorders of pregnancy

Abstract

Background: Hypertensive disorders of pregnancy (HDP) are a major cause of maternal morbidity in India. Their systemic effects are well-known, but the association with acute vestibular symptoms (AVS) like vertigo and dizziness is less studied in the Indian population, impacting maternal quality of life and safety.


Objectives: To determine the incidence of AVS in pregnant women with HDP and to investigate the association between HDP severity and AVS in a cohort from a tertiary care center in Dehradun.


Methods: A retrospective cohort study reviewed medical records of 328 antenatal patients who delivered between March 2022 to December 2022. Participants were categorized into a HDP group (n=112) and a normotensive control group (n=216). Data on demographics, HDP type, and documented AVS were extracted. Analysis used Chi-square tests and multivariate logistic regression.


Result: The incidence of AVS was significantly higher in the HDP group (39.3%) than in the control group (12.5%) (p < 0.001). Women with preeclampsia had a higher incidence (48.6%) than those with gestational hypertension (23.8%) (p = 0.008). HDP was independently associated with a 4.5-fold increased odds of AVS (Adjusted Odds Ratio: 4.52, 95% CI: 2.65-7.69).


Conclusions: HDP is a significant risk factor for AVS in this Indian cohort. Routine screening for vestibular complaints in pregnant women with HDP, particularly preeclampsia, is recommended for timely management.

Abstract 51 | Pdf Downloads 12

References

1. Gupta S, Gupta A. Hypertensive Disorders in Pregnancy: A Review from India. J ObstetGynaecol India. 2015 Dec;65(6):366-72. [This reference establishes the high burden and context of HDP in India.]
2. Sibai BM. Diagnosis and management of gestational hypertension and preeclampsia. Obstet Gynecol. 2003 Nov;102(5 Pt 1):1125-6. [A foundational international reference for diagnostic criteria.]
3. Ghosh S, Saha S, Gangopadhyay M. Neurological complications in eclampsia and preeclampsia: an observational study in a tertiary care institute of Eastern India. J Neurosci Rural Pract. 2014 Jul;5(3):215-9. [An Indian study detailing neurological manifestations, providing context for nervous system involvement.]
4. Yetiser S. The Vestibular System: Evaluation of the Vertiginous Patient. J Neurol Stroke. 2014;1(1):00002. [Provides the pathophysiological basis for vascular compromise affecting the vestibular system.]
5. Bhattacharyya N, Baugh RF, Orvidas L, Barrs D, Bronston LJ, Cass S, et al. Clinical practice guideline: benign paroxysmal positional vertigo. Otolaryngol Head Neck Surg. 2008 Nov;139(5 Suppl 4):S47-81. [An established guideline that helps differentiate types of dizziness.]
6. Singh S, Prakash J, Garg S. Quality of life in women with high-risk pregnancy in India. J ObstetGynaecol Res. 2018 Apr;44(4):665-672. [An Indian study highlighting the impact of pregnancy complications on quality of life, relevant to the burden of AVS.]
7. Rajalakshmi R, Gopalan K. Endothelial dysfunction in preeclampsia. Indian J Clin Biochem. 2005 Jul;20(2):174-81. [An Indian paper explaining the core vascular pathology of preeclampsia, supporting the ischemic hypothesis for AVS.]
8. Sundaram V, Geetha K, Niveditta G, Ganesh S. Autonomic dysfunction in preeclampsia: a case-control study. J Clin Diagn Res. 2014 Aug;8(8):OC01-OC03. [A South Indian study linking preeclampsia to autonomic instability, which can contribute to dizziness.]
9. Ghodke B, Pusukuru R, Mehta V. Association of Lipid Profile in Pregnancy with Preeclampsia. J Clin Diagn Res. 2016 Oct;10(10):QC12-QC15. [Another Indian study contributing to the regional understanding of preeclampsia's risk factors and associations.]