A REVIEW ON THE EMERGING POTENTIAL OF FLOATING MICROSPHERES IN GASTRORETENTIVE DRUG DELIVERY SYSTEMS
Main Article Content
Keywords
Floating drug delivery systems (FDDSs), Floating microspheres, Gastro retentive dosage forms, Gastroretentive Drug Delivery System.
Abstract
Oral drug delivery systems have to overcome a number of challenges in order to maintain drug release and extend the amount of time the medication is in the gastrointestinal tract until it has been fully consumed. A specific period of time later, fully released This procedure, called gastric emptying, It is emptied. Athletes who are having digestive problems can find it very beneficial. The upper small intestine provides a window for the absorption of nutrients. Drugs that are poorly soluble or unstable in intestinal fluids might benefit greatly from floating microspheres that improve drug retention and enable prolonged action in the stomach.
Floating drug delivery systems (FDDS) float in the stomach for a long time because of their lower bulk density than gastric fluids. Due to the possibility that floating microspheres in the stomach may lengthen a medication's retention time, the effects of the drug may remain longer. As a result, a longer drug retention time and a slower metabolism are required to assure long-term efficacy. FDDS dose forms are effective in situations of constipation and hyperactive bowel movement to elicit a significantly better reaction. Floating drug delivery systems (FDDSs) are helpful in these circumstances. They are anticipated to float on the stomach's contents for a considerable amount of time. Gastro retentive dosage forms are available in a variety of formats, such as tablets and capsules. Hollow microspheres are garnering a lot of interest due to their numerous potential uses in medicine delivery. Due to the drug substance being uniformly dispersed throughout the stomach juice, this prevents the drug from being released too soon. This review's objective is to examine floating microspheres approach in Gastro-retentive Drug Delivery System.
References
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2. Janjale, V. R., Patil, S. R., & Fegade, T. D. (2020). A Review on: Floating Microsphere. American Journal of Pharmaceutical Research, 10(02), 232-59.
3. Dighe, D. A., Choudhary, N. H., Thorat, M. S., Vir, P. R., Kumbhar, M. S., & Singh, M. C. (2012). Floating drug delivery system: A novel approach towards gastro retention. International Journal of Pharmaceutical and Chemical Science, 1(3), 779- 793.
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8. Gayathridevi M, J. Adlin Jino Nesalin and T. Tamizh Mani.Floating Microsphere: A Review.International Journal Of Research In Pharmacy And ChemistryIjrpc 2016, 6(3), 501-510.
9. Saxena, A., Gaur, K., Singh, V., Singh, R. K., & Dashora, A. (2014). Floating microspheres as drug delivery system. American Journal of Pharmacy and Pharmaceutical Sciences, 1(2), 27-36.
10. Garg, S., & Sharma, S. (2003). Gastroretentive drug delivery systems. Business Briefing: Pharmatech, 5(2), 160-162.
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12. Rubinstein, A., & Friend, D. R. (1994). Specific delivery to the gastrointestinal tract. polymeric site-specific Pharmacotherapy, Wiley, Chichester, 282-283.
13. Karande, A. D., & Yeole, P. G. (2006). Comparative assessment of different dissolution apparatus for floating drug delivery systems. system, 7, 9-12.
14. Iannuccelli, V., Coppi, G., Sansone, R., & Ferolla, G. (1998). Air compartment multiple-unit system for prolonged gastric residence. Part II. In vivo evaluation. International journal of pharmaceutics, 174(1-2), 55-62.
15. Sarmah, J., & Choudhury, A. (2020). Formulation and evaluation of gastro retentive floating tablets of ritonavir. Research Journal of Pharmacy and Technology, 13(9), 4099-4104.
16. Pant, S., Badola, A., & Kothiyal, P. (2016). A review on gastroretentive drug delivery system. Indian Journal of Pharmaceutical and Biological Research, 4(2), 1.
17. Lahoti, S. R., & Iftequar, S. (2011). An Overview of gastroretentive drug delivery system research. The International Research Journal of Pharmacy, 2(11), 80-87.
18. Biradar, V., Basavarajaiah, J. M., Win, M. T. T., Gudugunta, L., Suresh, K. V., Kumar, S. M., ... & Priya, L. (2019). In vitro evaluation of gastro retentive drug delivery system of lansoprazole. Research Journal of Pharmacy and Technology, 12(8), 3649- 3653.
19. Mehta, M., Pandey, P., Mahajan, S., & Satija, S. (2018). Gastro retentive drug delivery systems: An overview. Research Journal of Pharmacy and Technology, 11(5), 2157-2160.
20. Ayalasomayajula, L. U., Navya, K., Earle, R. R., & Pravallika, A. A. (2020). Review on non effervescent gastro retentive drug delivery systems-microballons. Asian Journal of Pharmaceutical Research, 10(4), 312-318.
21. Wagh, P. K., Ahirrao, S. P., & Kshirsagar, S. J. (2019). Novel mucoadhesive gastro retentive drug delivery system of ranitidine hydrochloride. Asian Journal of Pharmaceutical Research, 9(2), 80-86.
22. Suradkar, P., Mishra, R., & Nandgude, T. (2019). Overview on trends in development of gastroretentive drug delivery system. Research Journal of Pharmacy and Technology, 12(11), 5633-5640.
23. Shinkar, D. M., Suryawanshi, A. P., & Saudagar, R. B. (2016). Recent Approaches in Floating Drug Delivery System. Asian Journal of Pharmacy and Technology, 6(3), 141-147.
24. Kaushik, K., Chaurasia, D., Chaurasia, H., Mishra, S. K., & Bhardwaj, P. (2011). Development and characterization of floating alginate beads for gastroretentive drug delivery system. Acta Pharma Sci, 53(4), 551-562.
25. Bhowmik, D., Bhanot, R., Gautam, D., Rai, P., & Kumar, K. P. (2018). Gastro Retentive Drug Delivery Systems-a Novel Approaches of Controlled Drug Delivery Systems. Research Journal of Science and Technology, 10(2), 145-156.
26. Shashank C, Prabha K, Sunil S, Vipin Kumar A. Approaches to increase the gastric residence time: floating drug delivery systems-a review. Asian J Pharm Clin Res. 2013;6(3):1-9.
27. Arunachalam A, Karthikeyan M, Konam K, Prasad H, Sethuraman S, Ashutoshkumar S, et al. Floating drug delivery systems: A review. Int J Res Pharm Sci. 2011;2(1):76-83.
28. Mayavanshi A, Gajjar S. Floating drug delivery systems to increase gastric retention of drugs: A Review. Research Journal of Pharmacy and Technology. 2008;1(4):345-8.
29. Chowdary K, Chaitanya C. Recent research on floating drug delivery systems-a review. Journal of Global Trends in Pharmaceutical Sciences. 2014;5(1):1361-73.
30. Kumari B, Khansili A, Phougat P, Kumar M. Comprehensive review of the role of acrylic acid derivative polymers in floating drug delivery system. Polimery w Medycynie. 2019;49(2):71-9.
31. Arora S, Ali J, Ahuja A, Khar RK, Baboota S. Floating drug delivery systems: a review. Aaps PharmSciTech. 2005;6(3):E372-E90.
32. Riahi A. Oil-in-water emulsion-solvent evaporation fabrication of polycaprolactone containing piroxicam for drug release. Medbiotech Journal. 2018;2(01):14-20.
33. Hamishehkar H, Emami J, Najafabadi AR, Gilani K, Minaiyan M, Mahdavi H, et al. The effect of formulation variables on the characteristics of insulin-loaded poly (lactic-co-glycolic acid) microspheres prepared by a single phase oil in oil solvent evaporation method. Colloids and Surfaces B: Biointerfaces. 2009;74(1):340-9.
34. Abbas AK, Alhamdany AT. Floating Microspheres of Enalapril Maleate as a Developed Controlled Release Dosage Form: Investigation of the Effect of an Ionotropic Gelation Technique. Turkish Journal of Pharmaceutical Sciences. 2020;17(2):159.
35. Jagtap Y, Bhujbal R, Ranade A, Ranpise N. Effect of various polymers concentrations on physicochemical properties of floating microspheres. Indian journal of pharmaceutical sciences. 2012;74(6):512.
36. Nila M, Sudhir M, Cinu T, Aleykutty N, Jose S. Floating microspheres of carvedilol as gastro retentive drug delivery system: 32 full factorial design and in vitro evaluation. Drug delivery. 2014;21(2):110-7.
37. Shwetha S, Kamath K, Kumar S. Design and evaluation of floating microspheres of Rabeprazole sodium. International Journal of Pharmacy and Pharmaceutical Sciences. 2012;4(3):104-20.
38. Dey S, Kumar D, Kumar S, Sreenivas S, Rahul V, Samal HB. Formulation, charecterization and invitro evaluation of floating microspheres of nateglinide. International journal of pharma and bio science. 2011;2(1):147-56.
39. Kumar K, Rai A. Development and evaluation of floating microspheres of curcumin. Tropical journal of pharmaceutical research. 2012;11(5):713-9.
40. El-Nahas H, Hosny K. Chitosan-based floating microspheres of trimetazidin dihydrochloride; preparation and in vitro characterization. Indian journal of pharmaceutical sciences. 2011;73(4):397.
41. Mukund JY, Kantilal BR, Sudhakar RN. Floating microspheres: a review. Brazilian Journal of Pharmaceutical Sciences. 2012;48:17-30.
42. KUMAR A, SRIVASTAVA R. In Vitro In Vivo Studies On Floating Microspheres For Gastroretentive Drug Delivery System: A Review. Asian Journal of Pharmaceutical and Clinical Research. 2021:13-26.
43. Rani R, Kumar M, Yadav N, Bhatt S, Malik A, Kumari B, et al. Recent Advances in the Development of Floating Microspheres for the Treatment of Gastric Ulcers. Recent Advances in the Development of Floating Microspheres for. 2020;29(5):3613-27.
44. Jain SK, Agrawal GP, Jain NK. Evaluation of porous carrier-based floating orlistat microspheres for gastric delivery. AAPS pharmscitech. 2006;7(4):E54-E62.
45. Garg R, Gupta G. Gastroretentive floating microspheres of silymarin: preparation and in vitro evaluation. Tropical journal of pharmaceutical research. 2010;9(1).
46. Palanivelu M, Prashob A, Ramalingam N, Muniyandi SK. Formulation and Evaluation of Ranitidine Hydrochloride Loaded Floating Microspheres for the Treatment of Gastric Ulcer.
47. Patel A, Ray S, Thakur RS. In vitro Evaluation and Optimization of Controlled Release Floating Drug Delivery System of Metformin Hydrochloride. DARU Journal. 2006; 14(2): 57-64.
48. Fabregas JL, Garcia N. Invitro Studies on Buccoadhesive Tablet Formulations of Hydro Cortisone Hemisuccinate. Drug Dev.Ind.Pharm. 1995; 21(14): 1689-1696.
49. Rathbone MJ. Purve R. Ghazati FA, In Vivo Techniques for Studying the Oral Mucosa Absorption Characteristics of Drugs in Animals and Humans. In Rathbone, M.J. (Ed.). Oral Mucosal Delivery Systems, Marcel Dekker Inc. Newyork. 1996; 121-156.
50. Lu MF. Delivery of Rennin Inhibitors Through Mouth Mucosa. Drug Dev.Ind.Pharm. 1996; 22(11): 1167-1171.
51. Yukimatsu K, Nozaki Y. Development of a Transmucosal Controlled Release Device for Systemic Delivery of Antianginal Drugs Pharmacokinetics and Pharmacodynamics. Drug Dev.Ind.Pharm. 1994; 20(4): 503-534.
52. Hussain, MA. Aungst BJ. Kearney A. Buccal and Oral Bioavailability of Naloxone and Naltrexone in Rats. Int. J.Pharm. 197; 36:127.
53. Soppimath KS. Microspheres as Floating Drug Delivery Systems to Increase Gastric Retention of Drugs. Drug Metab. Rev. 2001; 33: 149-160.
54. Srivastava AK. Ridhurkar DN. Wadhwa S. Floating Microspheres of Cimetidine: Formulation, Characterization and In Vitro Evaluation. Acta Pharm. 2005; 55: 277-285.
55. Stanley SD. Formulation Strategies for Absorption Windows. DDT. 2005; 10: 249-257.
56. Streubel A. Siepmann J. Bodmeier R. Floating Microparticles Based on Low Density Foam Powder. Int. J. Pharm. 2002; 241: 279-292.
57. Sarode. Formulation and Evaluation of Floating Microspheres of Glipizide. J. Chem. Pharm. Res. 2011; 3(3): 775-783.
2. Janjale, V. R., Patil, S. R., & Fegade, T. D. (2020). A Review on: Floating Microsphere. American Journal of Pharmaceutical Research, 10(02), 232-59.
3. Dighe, D. A., Choudhary, N. H., Thorat, M. S., Vir, P. R., Kumbhar, M. S., & Singh, M. C. (2012). Floating drug delivery system: A novel approach towards gastro retention. International Journal of Pharmaceutical and Chemical Science, 1(3), 779- 793.
4. Jain, N. K. (Ed.). (1997). Controlled and novel drug delivery (pp. 236-237). New Delhi: CBS publishers & distributors.
5. Ramaiyan Dhanapal and J. Vijaya Ratna.Floating Drug Delivery Systems: A Novel Approach .International Journal of Pharmaceutical Development & TechnologyRamaiyan Dhanapal. et al. / IJPDT / 2 (1), 2012, 29-36.
6. Choudhary, M., Tiwari, C., Chahar, R. K., Malik, P., Jaiswal, P. K., & Chauhan, R. (2022). Floating Drug Delivery System: As A Novel Approach for Drug Delivery. Journal of Drug Delivery and Therapeutics, 12(6), 210-218.
7. Shah, S., & Pandya, S. (2010). A novel approach in gastro retentive drug delivery system: floating drug delivery system. International Journal of Pharmaceutical Sciences and Research, 1(6), 7-18.
8. Gayathridevi M, J. Adlin Jino Nesalin and T. Tamizh Mani.Floating Microsphere: A Review.International Journal Of Research In Pharmacy And ChemistryIjrpc 2016, 6(3), 501-510.
9. Saxena, A., Gaur, K., Singh, V., Singh, R. K., & Dashora, A. (2014). Floating microspheres as drug delivery system. American Journal of Pharmacy and Pharmaceutical Sciences, 1(2), 27-36.
10. Garg, S., & Sharma, S. (2003). Gastroretentive drug delivery systems. Business Briefing: Pharmatech, 5(2), 160-162.
11. Hirtz, J. (1985). The gastrointestinal absorption of drugs in man: a review of current concepts and methods of investigation. British journal of clinical pharmacology, 19(S2), 77S-83S.
12. Rubinstein, A., & Friend, D. R. (1994). Specific delivery to the gastrointestinal tract. polymeric site-specific Pharmacotherapy, Wiley, Chichester, 282-283.
13. Karande, A. D., & Yeole, P. G. (2006). Comparative assessment of different dissolution apparatus for floating drug delivery systems. system, 7, 9-12.
14. Iannuccelli, V., Coppi, G., Sansone, R., & Ferolla, G. (1998). Air compartment multiple-unit system for prolonged gastric residence. Part II. In vivo evaluation. International journal of pharmaceutics, 174(1-2), 55-62.
15. Sarmah, J., & Choudhury, A. (2020). Formulation and evaluation of gastro retentive floating tablets of ritonavir. Research Journal of Pharmacy and Technology, 13(9), 4099-4104.
16. Pant, S., Badola, A., & Kothiyal, P. (2016). A review on gastroretentive drug delivery system. Indian Journal of Pharmaceutical and Biological Research, 4(2), 1.
17. Lahoti, S. R., & Iftequar, S. (2011). An Overview of gastroretentive drug delivery system research. The International Research Journal of Pharmacy, 2(11), 80-87.
18. Biradar, V., Basavarajaiah, J. M., Win, M. T. T., Gudugunta, L., Suresh, K. V., Kumar, S. M., ... & Priya, L. (2019). In vitro evaluation of gastro retentive drug delivery system of lansoprazole. Research Journal of Pharmacy and Technology, 12(8), 3649- 3653.
19. Mehta, M., Pandey, P., Mahajan, S., & Satija, S. (2018). Gastro retentive drug delivery systems: An overview. Research Journal of Pharmacy and Technology, 11(5), 2157-2160.
20. Ayalasomayajula, L. U., Navya, K., Earle, R. R., & Pravallika, A. A. (2020). Review on non effervescent gastro retentive drug delivery systems-microballons. Asian Journal of Pharmaceutical Research, 10(4), 312-318.
21. Wagh, P. K., Ahirrao, S. P., & Kshirsagar, S. J. (2019). Novel mucoadhesive gastro retentive drug delivery system of ranitidine hydrochloride. Asian Journal of Pharmaceutical Research, 9(2), 80-86.
22. Suradkar, P., Mishra, R., & Nandgude, T. (2019). Overview on trends in development of gastroretentive drug delivery system. Research Journal of Pharmacy and Technology, 12(11), 5633-5640.
23. Shinkar, D. M., Suryawanshi, A. P., & Saudagar, R. B. (2016). Recent Approaches in Floating Drug Delivery System. Asian Journal of Pharmacy and Technology, 6(3), 141-147.
24. Kaushik, K., Chaurasia, D., Chaurasia, H., Mishra, S. K., & Bhardwaj, P. (2011). Development and characterization of floating alginate beads for gastroretentive drug delivery system. Acta Pharma Sci, 53(4), 551-562.
25. Bhowmik, D., Bhanot, R., Gautam, D., Rai, P., & Kumar, K. P. (2018). Gastro Retentive Drug Delivery Systems-a Novel Approaches of Controlled Drug Delivery Systems. Research Journal of Science and Technology, 10(2), 145-156.
26. Shashank C, Prabha K, Sunil S, Vipin Kumar A. Approaches to increase the gastric residence time: floating drug delivery systems-a review. Asian J Pharm Clin Res. 2013;6(3):1-9.
27. Arunachalam A, Karthikeyan M, Konam K, Prasad H, Sethuraman S, Ashutoshkumar S, et al. Floating drug delivery systems: A review. Int J Res Pharm Sci. 2011;2(1):76-83.
28. Mayavanshi A, Gajjar S. Floating drug delivery systems to increase gastric retention of drugs: A Review. Research Journal of Pharmacy and Technology. 2008;1(4):345-8.
29. Chowdary K, Chaitanya C. Recent research on floating drug delivery systems-a review. Journal of Global Trends in Pharmaceutical Sciences. 2014;5(1):1361-73.
30. Kumari B, Khansili A, Phougat P, Kumar M. Comprehensive review of the role of acrylic acid derivative polymers in floating drug delivery system. Polimery w Medycynie. 2019;49(2):71-9.
31. Arora S, Ali J, Ahuja A, Khar RK, Baboota S. Floating drug delivery systems: a review. Aaps PharmSciTech. 2005;6(3):E372-E90.
32. Riahi A. Oil-in-water emulsion-solvent evaporation fabrication of polycaprolactone containing piroxicam for drug release. Medbiotech Journal. 2018;2(01):14-20.
33. Hamishehkar H, Emami J, Najafabadi AR, Gilani K, Minaiyan M, Mahdavi H, et al. The effect of formulation variables on the characteristics of insulin-loaded poly (lactic-co-glycolic acid) microspheres prepared by a single phase oil in oil solvent evaporation method. Colloids and Surfaces B: Biointerfaces. 2009;74(1):340-9.
34. Abbas AK, Alhamdany AT. Floating Microspheres of Enalapril Maleate as a Developed Controlled Release Dosage Form: Investigation of the Effect of an Ionotropic Gelation Technique. Turkish Journal of Pharmaceutical Sciences. 2020;17(2):159.
35. Jagtap Y, Bhujbal R, Ranade A, Ranpise N. Effect of various polymers concentrations on physicochemical properties of floating microspheres. Indian journal of pharmaceutical sciences. 2012;74(6):512.
36. Nila M, Sudhir M, Cinu T, Aleykutty N, Jose S. Floating microspheres of carvedilol as gastro retentive drug delivery system: 32 full factorial design and in vitro evaluation. Drug delivery. 2014;21(2):110-7.
37. Shwetha S, Kamath K, Kumar S. Design and evaluation of floating microspheres of Rabeprazole sodium. International Journal of Pharmacy and Pharmaceutical Sciences. 2012;4(3):104-20.
38. Dey S, Kumar D, Kumar S, Sreenivas S, Rahul V, Samal HB. Formulation, charecterization and invitro evaluation of floating microspheres of nateglinide. International journal of pharma and bio science. 2011;2(1):147-56.
39. Kumar K, Rai A. Development and evaluation of floating microspheres of curcumin. Tropical journal of pharmaceutical research. 2012;11(5):713-9.
40. El-Nahas H, Hosny K. Chitosan-based floating microspheres of trimetazidin dihydrochloride; preparation and in vitro characterization. Indian journal of pharmaceutical sciences. 2011;73(4):397.
41. Mukund JY, Kantilal BR, Sudhakar RN. Floating microspheres: a review. Brazilian Journal of Pharmaceutical Sciences. 2012;48:17-30.
42. KUMAR A, SRIVASTAVA R. In Vitro In Vivo Studies On Floating Microspheres For Gastroretentive Drug Delivery System: A Review. Asian Journal of Pharmaceutical and Clinical Research. 2021:13-26.
43. Rani R, Kumar M, Yadav N, Bhatt S, Malik A, Kumari B, et al. Recent Advances in the Development of Floating Microspheres for the Treatment of Gastric Ulcers. Recent Advances in the Development of Floating Microspheres for. 2020;29(5):3613-27.
44. Jain SK, Agrawal GP, Jain NK. Evaluation of porous carrier-based floating orlistat microspheres for gastric delivery. AAPS pharmscitech. 2006;7(4):E54-E62.
45. Garg R, Gupta G. Gastroretentive floating microspheres of silymarin: preparation and in vitro evaluation. Tropical journal of pharmaceutical research. 2010;9(1).
46. Palanivelu M, Prashob A, Ramalingam N, Muniyandi SK. Formulation and Evaluation of Ranitidine Hydrochloride Loaded Floating Microspheres for the Treatment of Gastric Ulcer.
47. Patel A, Ray S, Thakur RS. In vitro Evaluation and Optimization of Controlled Release Floating Drug Delivery System of Metformin Hydrochloride. DARU Journal. 2006; 14(2): 57-64.
48. Fabregas JL, Garcia N. Invitro Studies on Buccoadhesive Tablet Formulations of Hydro Cortisone Hemisuccinate. Drug Dev.Ind.Pharm. 1995; 21(14): 1689-1696.
49. Rathbone MJ. Purve R. Ghazati FA, In Vivo Techniques for Studying the Oral Mucosa Absorption Characteristics of Drugs in Animals and Humans. In Rathbone, M.J. (Ed.). Oral Mucosal Delivery Systems, Marcel Dekker Inc. Newyork. 1996; 121-156.
50. Lu MF. Delivery of Rennin Inhibitors Through Mouth Mucosa. Drug Dev.Ind.Pharm. 1996; 22(11): 1167-1171.
51. Yukimatsu K, Nozaki Y. Development of a Transmucosal Controlled Release Device for Systemic Delivery of Antianginal Drugs Pharmacokinetics and Pharmacodynamics. Drug Dev.Ind.Pharm. 1994; 20(4): 503-534.
52. Hussain, MA. Aungst BJ. Kearney A. Buccal and Oral Bioavailability of Naloxone and Naltrexone in Rats. Int. J.Pharm. 197; 36:127.
53. Soppimath KS. Microspheres as Floating Drug Delivery Systems to Increase Gastric Retention of Drugs. Drug Metab. Rev. 2001; 33: 149-160.
54. Srivastava AK. Ridhurkar DN. Wadhwa S. Floating Microspheres of Cimetidine: Formulation, Characterization and In Vitro Evaluation. Acta Pharm. 2005; 55: 277-285.
55. Stanley SD. Formulation Strategies for Absorption Windows. DDT. 2005; 10: 249-257.
56. Streubel A. Siepmann J. Bodmeier R. Floating Microparticles Based on Low Density Foam Powder. Int. J. Pharm. 2002; 241: 279-292.
57. Sarode. Formulation and Evaluation of Floating Microspheres of Glipizide. J. Chem. Pharm. Res. 2011; 3(3): 775-783.
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Oct 01, 2025
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Kuldipsinh Chauhan, Dr.Shweta Paroha, & Dr.Pragnesh Patani. (2025). A REVIEW ON THE EMERGING POTENTIAL OF FLOATING MICROSPHERES IN GASTRORETENTIVE DRUG DELIVERY SYSTEMS. Journal of Population Therapeutics and Clinical Pharmacology, 32(7), 1694-1708. https://doi.org/10.53555/kkskxe69
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Author Biographies
Kuldipsinh Chauhan
Khyati College of Pharmacy, Palodia, Ahemdabad
Dr.Shweta Paroha
Khyati College of Pharmacy, Palodia, Ahemdabad
Dr.Pragnesh Patani
Khyati College of Pharmacy, Palodia, Ahemdabad
How to Cite
Kuldipsinh Chauhan, Dr.Shweta Paroha, & Dr.Pragnesh Patani. (2025). A REVIEW ON THE EMERGING POTENTIAL OF FLOATING MICROSPHERES IN GASTRORETENTIVE DRUG DELIVERY SYSTEMS. Journal of Population Therapeutics and Clinical Pharmacology, 32(7), 1694-1708. https://doi.org/10.53555/kkskxe69