COMPARATIVE STUDY OF MUSCLE RELAXANTS AND NSAIDS IN TEMPOROMANDIBULAR JOINT DYSFUNCTION SYNDROME
Main Article Content
Keywords
Temporomandibular joint dysfunction, NSAIDs, muscle relaxant, ibuprofen, diazepam
Abstract
Background: Temporomandibular joint dysfunction (TMJD) affects the joint and associated musculoskeletal structures, often causing pain and functional limitation. NSAIDs and muscle relaxants are commonly used for symptom relief, but few comparative studies exist.
Aim: To assess and compare the clinical efficacy of ibuprofen (NSAID) and diazepam (muscle relaxant) in TMJD treatment.
Methods: This observational study included 54 patients diagnosed with TMJD. Group A received ibuprofen 400 mg twice daily, and Group B received diazepam 5 mg once daily. Baseline and one-month follow-up assessments included pain (VAS score) and maximal mouth opening (MMO). Statistical analysis employed paired t-tests, independent t-tests, and chi-square tests. Significance was set at p<0.05.
Results: There were no significant differences in age, sex distribution, or baseline VAS/MMO scores between groups. Both treatments significantly reduced pain and improved MMO. Post-treatment VAS was lower in the NSAID group (2.48 ± 1.01) compared to the diazepam group (3.59 ± 1.00), with a significant difference (p=0.00009). MMO improvement was not significantly different between groups (p=0.06).
Conclusion: Both NSAIDs and muscle relaxants are effective for TMJD symptom relief, with ibuprofen showing superior pain reduction. NSAIDs may be preferred as first-line pharmacotherapy in TMJD.
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Prohalad Kumar Paul
Consultant, Dhaka Dental College, Dhaka, Bangladesh
Md. Asaduzzaman
Professor, Department of Oral & Maxillofacial Surgery, Bangladesh Medical University (Ex-BSMMU), Dhaka, Bangladesh
Md. Wares Uddin
Associate Professor, Department of Oral & Maxillofacial Surgery, Bangladesh Medical University (Ex-BSMMU), Dhaka, Bangladesh,
Shamiul Alam
Associate Professor, Department of Oral & Maxillofacial Surgery, Bangladesh Medical University (Ex-BSMMU), Dhaka, Bangladesh,
Wahidujjaman
Assistant Professor, Department of Oral & Maxillofacial Surgery, Bangladesh Medical University (Ex- BSMMU), Dhaka, Bangladesh,
Ruman Banik
Assistant Professor, Department of Oral & Maxillofacial Surgery, Bangladesh Medical University (Ex- BSMMU), Dhaka, Bangladesh,
Mahmudul Hasan
Assistant Professor, Department of Oral & Maxillofacial Surgery, Bangladesh Medical University (Ex- BSMMU), Dhaka, Bangladesh,
Ashik Abdullah Imon
Assistant Professor, Department of Oral & Maxillofacial Surgery, Bangladesh Medical University (Ex-BSMMU), Dhaka, Bangladesh,