TO EVALUATE THE OUTCOMES OF INJECTABLE PLATELET RICH FIBRIN IN TREATING FEMALE PATTERN HAIR LOSS
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Abstract
Background: Nowadays, a very common hair loss disorder is spreading in adults which is called female androgenic alopecia (AGA). It is also referred to as female pattern hair loss (FPHL). This disorder is common in about 40% of females by 70 years of age. FPHL occurs when terminal hair on the frontal as well as the crown areas start getting thinner. The only FDA-approved treatment for FPHL is topical minoxidil (2% and 5%). There are several other options as well such as laser therapy, oral spironolactone, hair transplant, and finasteride (oral and topical). Recently, the study of APAs (autologous platelet aggregates) have proved that it can be a possible treatment for FPHL. PRP (platelet-rich plasma) injections are also similar to APAs. There is a new version of PRP which is called PRF (platelet-rich fibrin).
Objective: To Evaluate the Outcomes of Injectable Platelet Rich Fibrin In Treating Female Pattern Hair Loss
Methodology: This study is a controlled, single-center, prospective case series of females who are all adults. All the females were having FPHL and wanted to have PRF scalp injections. All the females who were aged more than 18 years old, were healthy, and had no history of any surgical treatment for hair loss were eligible for this research. FPHL was diagnosed based on scalp digital microscopy and Ludwig hair loss classification. Medical history, digital scalp imaging, and hair pull test were obtained in the first visit along with standardised pictures. Participants underwent three i Injectable Platelet Rich Fibrin scalp treatments. SPSS was used to analyse the data. A significant p-value was considered to be less than 0.05.
Results: There were a total of 20 female participants of this study. All the females were suffering from female pattern hair loss. All the females who were aged more than 18 years old (mean = 45.1). Their ages ranged from 32 years to 74 years (mean = 37.1). The mean number of hairs pulled were decreased throughout the study period. Through clinical photography, a clear improvement was seen in hair thickness and reduction of visible scalp.
Conclusion: In summary, Injectable Platelet Rich Fibrin is an effective and safe treatment for FPHL.
References
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Jameel Sayed
Specialist Dermatologist, Ultra Cosmetic Medical Center, Doha, Qatar
Maria Farooqi
Consultant Dermatologist, King Abdullah Medical City Makkah Kingdom of Saudi Arabia
Omar Imran
Dow International Medical College Karachi Pakistan
Sufia Sayed
Royal College of Surgeons in Ireland, Bahrain