HISTOMORPHOLOGICAL STUDY OF LUNGS IN CASE OF DEATH IN COVID PANDEMIC OUTBREAK – AN AUTOPSY STUDY IN A TERTIARY CARE CENTRE.
Main Article Content
Keywords
Abstract
The Coronaviridae viral family typically causes respiratory disease in human are enveloped virus comprising single-stranded RNA. Coronavirus disease 2019 (COVID-19) posed a pandemic in the form of severe acute respiratory syndrome (SARS)-which led to a major health disaster all over the world.
References
1. Suess C, Hausmann R. Gross and histopathological pulmonary findings in a COVID-19 associated death during self-isolation. Int J Legal Med. 2020;134(4):1285-1290.
2. Corman VM, Lienau J, Witzenrath M (2019) Coronaviren als Ursache respiratorischer Infektionen [coronaviruses as the cause of respiratory infections]. Internist (Berl) 60:1136–1145
3. Wu F, Zhao S, Yu B, Chen YM, Wang W et.al. A new coronavirus associated with human respiratory disease in China. Nature, 579:265–269.
4. Zhou P, Yang XL, Wang XG, Hu B, Zhang L, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 579:270–273.
5. Lukassen S, Chua RL, Trefzer T, Kahn NC, Schneider MA, et al. SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells. EMBO J 39:e105114.
6. Zhou F, Yu T, Du R, Fan G, Liu Y, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 395:1054–1062.
7. GuanWJ, Ni ZY, Hu Y, LiangWH, Ou CQ, et al. China Medical Treatment Expert Group for Covid-19 (2020) Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 382:1708–1720.
8. Dramé M, Tabue Teguo M, Proye E, Hequet F, Hentzien M, Kanagaratnam L, Godaert L. Should RT-PCR be considered a gold standard in the diagnosis of COVID-19? J Med Virol. 2020 May 8:10.1002/jmv.25996.
9. Wu C, Chen X, Cai Y, Xia J, Zhou X, et al. Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia inWuhan, China. JAMAInternMed. https://doi.org/10.1001/jamainternmed.2020.0994
10. Zhang H, Zhou P, Wei Y, Yue H,Wang Y, et al. Histopathologic changes and SARS-CoV-2 Immunostaining in the lung of a patient with COVID-19. Ann Intern Med 172:629–632.
11. S. Caramaschi et al. Histopathological findings and clinicopathologic correlation in COVID-19: a systematic review Modern Pathology (2021) 34:1614–1633.
12. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395: 1054–62.
2. Corman VM, Lienau J, Witzenrath M (2019) Coronaviren als Ursache respiratorischer Infektionen [coronaviruses as the cause of respiratory infections]. Internist (Berl) 60:1136–1145
3. Wu F, Zhao S, Yu B, Chen YM, Wang W et.al. A new coronavirus associated with human respiratory disease in China. Nature, 579:265–269.
4. Zhou P, Yang XL, Wang XG, Hu B, Zhang L, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 579:270–273.
5. Lukassen S, Chua RL, Trefzer T, Kahn NC, Schneider MA, et al. SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells. EMBO J 39:e105114.
6. Zhou F, Yu T, Du R, Fan G, Liu Y, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 395:1054–1062.
7. GuanWJ, Ni ZY, Hu Y, LiangWH, Ou CQ, et al. China Medical Treatment Expert Group for Covid-19 (2020) Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 382:1708–1720.
8. Dramé M, Tabue Teguo M, Proye E, Hequet F, Hentzien M, Kanagaratnam L, Godaert L. Should RT-PCR be considered a gold standard in the diagnosis of COVID-19? J Med Virol. 2020 May 8:10.1002/jmv.25996.
9. Wu C, Chen X, Cai Y, Xia J, Zhou X, et al. Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia inWuhan, China. JAMAInternMed. https://doi.org/10.1001/jamainternmed.2020.0994
10. Zhang H, Zhou P, Wei Y, Yue H,Wang Y, et al. Histopathologic changes and SARS-CoV-2 Immunostaining in the lung of a patient with COVID-19. Ann Intern Med 172:629–632.
11. S. Caramaschi et al. Histopathological findings and clinicopathologic correlation in COVID-19: a systematic review Modern Pathology (2021) 34:1614–1633.
12. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395: 1054–62.