USE OF BIOACTIVE DENTAL MATERIALS IN TREATMENT OF ORAL LICHEN PLANUS
Main Article Content
Keywords
Oral lichen planus, bioactive dental materials, platelet-rich fibrin, aloe vera, corticosteroids, mucosal healing.
Abstract
: Oral lichen planus (OLP) is a noninfectious inflammatory disease of the oral mucosa of unknown aetiology. Drugs conventionally used in corticosteroid treatment provide temporary relief, but they mostly lead to recurrence and severity. The benefits of bioactive dental materials include their regenerative and immunomodulatory properties, resulting in improved outcomes.
Objective: This study aimed to determine the clinical effectiveness of bioactive dental materials in treating oral lichen planus compared to conventional steroid-based therapy.
Material and Methods: This is a randomised clinical study conducted at Department of Oral Medicine, Ayub Medical Institute Abbottabad, Pakistan in the duration from November, 2024 to April, 2025. Sixty cases of proven OLP were categorised into two groups: Group A was a group where PRF and aloe vera gel were injected, and Group B was the clobetasol propionate. The six-week assessment was based on Thongprasom scores, VAS, and OHIP-14 to measure outcomes.
Result: Group A experienced significantly more improvement in lesion resolution, pain reduction and quality-of-life improvement as compared to Group B (p < 0.001), with no adverse effects reported.
Conclusion: Bioactive dental materials proved to have the best therapeutic values and are capable substitutes for the standard treatment of OLP.
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Dr Ayesha Bibi
assistant Professor, Department Of Oral Medicine, Ayub Medical Institute Abbottabad, Pakistan
Dr Rabia Anwar
Assistant Professor, Department Of Dental Materials, Ayub Medical College, Abbotabad, Pakistan