CASE SERIES OF EXTRAPULMONARY SMALL CELL CARCINOMA IN A TERTIARY CARE CENTER OF ROHILKHAND REGION

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Loitongbam Tappisana Chanu
Tanu Agrawal
Surabhi Pandey
Era Bhardwaj
Bir Parkash

Keywords

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Abstract

Extra Pulmonary Small Cell Carcinoma (EPSCC) is a rare, aggressive malignancy that originates outside of the lungs, yet shares histopathological features with Small Cell Lung Carcinoma (SCLC). Extrapulmonary sites constitute 5.8% of all small cell carcinoma (SCC) cases. Unlike its pulmonary counterpart, which is more commonly recognized, EPSCC typically originates in other anatomical sites, including the gastrointestinal tract, genitourinary system, and skeletal muscular system.1,2

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References

1. Bhowmik D, et al. Epidemiology and treatment of extrapulmonary small cell cancer. Journal of Oncology. 2020.
2. Mandish S, et al. Extrapulmonary Small Cell Carcinoma: Epidemiology, Prognostic Variables, and Overall Survival. International Journal of Radiation Oncology, Biology, Physics. 105: E259
3. Wong YN, Jack RH, Mak V, Henrik M, Davies EA (2009). The epidemiology and survival of extrapulmonary small cell carcinoma in South East England, 1970-2004. BMC Cancer, 9, 209
4. Brennan SM, Gregory DL, Stillie A, et al (2010). Should extrapulmonary small cell cancer be managed like small cell lung cancer? Cancer, 116, 888-95
5. Lin IH, Hwang CF, Huang HY, Chien CY (2007). Small cell carcinoma of the nasopharynx. Acta Otolaryngol, 127, 206-8.
6. Ochsenreither S, Marnitz-Schultze S, Schneider A, et al (2009). Extrapulmonary small cell carcinoma (EPSCC): 10 years’ multi-disciplinary experience at Charité. Anticancer Res, 29, 3411–5.
7. Khorana AA, Francis CW, Putterman J. Bone metastasis and survival outcomes in patients with extrapulmonary small cell cancer. Cancer. 2019; 125: 623-630
8. Frazier SR, Kaplan PA, Loy TS. The pathology of extrapulmonary small cell carcinoma. Semin Oncol 2007; 34:30–38
9. Choong NWW. Small cell carcinoma of the urinary bladder. Mayo Clinic Experi Cancer. 2005;103(6):1172–1178. doi: 10.1002/cncr.20903
10. Casas F. Primary small cell carcinoma of the esophagus: a review of the literature with emphasis on therapy and prognosis. Cancer. 1997;80(8):1366–1372
11. Cicin I. Extrapulmonary small-cell carcinoma compared with small-cell lung carcinoma: a retrospective single-center study. Cancer. 2007;110(5):1068–1076. doi: 10.1002/cncr.22887
12. Kim JH. Extrapulmonary small-cell carcinoma: a single-institution experience. Jpn J Clin Oncol. 2004;34(5):250–254. doi: 10.1093/jjco/hyh052
13. Haider K. Extrapulmonary small cell cancer: a Canadian province’s experience. Cancer. 2006;107(9):2262–2269. doi: 10.1002/cncr.22235
14. Dakhil CS, Wick JA, Kumar AK, Satyan MT, Neupane P. Extrapulmonary small cell carcinoma: the University of Kansas experience and review of literature. Med Oncol. 2014 Oct;31(10):187. doi:10.1007/s12032-014-0187-1.