ASSESSING THE ROLE OF HIGH-DOSE VITAMIN C IN CRITICALLY ILL PATIENTS WITH COVID-19
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Keywords
COVID-19, High-dose vitamin C, Critically ill, Inflammation, ICU mortality.
Abstract
Introduction: COVID-19 patients in critical condition can suffer a lot of inflammation and oxidative stress, making their prognosis poor. Clinicians propose that HDIVC can be an additional therapy, as its antioxidant and immunomodulatory properties may help patients.
Objective: This study aimed to examine how HDIVC affects the outcomes of critically ill patients with COVID-19.
Materials and Methods: A prospective cohort study was conducted at Department of Pulmonology, Saidu Medical College and Saidu Group of Teaching Hospital Swat, Pakistan, from January, 2024 to June, 2024. Only ill COVID-19 patients treated with usual procedures and either HDIVC or no HDIVC were studied. The team looked at measurable measurements of inflammation and how patients recovered.
Results: After HDIVC administration, the ICU death rate, time spent in the ICU, and mechanical ventilation time were reduced. Among the inflammatory markers, including CRP, D-dimer, and ferritin, levels decreased more in the HDIVC group than in the control group.
Conclusion: HDIVC appears to make treatment safer and more effective for critically ill COVID-19 patients. Repeated larger studies should confirm the results found in this research.
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Obaidullah
Senior registrar Department of Medicine, Timergara Teaching Hospital Dir Lower, Pakistan
Akhtar Ali Khan
Assistant Professor, Department of Pulmonology, Saidu Medical College and Saidu Group of Teaching Hospital Swat, Pakistan
Tehreem Khan
MBBS, Nishter Medical University, Multan Pakistan, Master in Medicine (Infection and Immunity), The University of Sydney, Australia
Niaz Ahmed
Professor, Department Medicine, Shaheed Mohtarma Benazir Bhutto Medical College Lyari
Karachi and Sindh Government Lyari General Hospital, Pakistan
Sajjad ul Hasan
Assistant Professor, Department of Community Medicine, Amna Inayat Medical College, Sheikhupura, Punjab, Pakistan
Momin Khan
Associate Professor, Medicine Department, Saidu Group of Teaching Hospital Swat, pakistan