STUDY OF PREDICTORS OF WOUND DEHISCENCE IN MAJOR ABDOMINAL SURGERIES
Main Article Content
Keywords
Wound dehiscence, abdominal surgery, risk factors, hypoalbuminemia, surgical site infection, emergency laparotomy, postoperative complications
Abstract
Wound dehiscence is a serious postoperative complication following major abdominal surgeries, contributing to increased morbidity, prolonged hospital stays, and elevated healthcare costs. Identifying predictive risk factors is essential for early recognition and prevention.
Objective: To evaluate the incidence of wound dehiscence and identify significant preoperative, intraoperative, and postoperative predictors in patients undergoing major abdominal surgeries at a tertiary care hospital.
Methods: This prospective observational study was conducted over one year in the Department of Surgery, Maharshi Vishwamitra Autonomous State Medical College (MV ASMC), Ghazipur, Uttar Pradesh. A total of 420 adult patients undergoing major abdominal surgeries were enrolled. Data on demographics, comorbidities, surgical details, and postoperative complications were collected. Wound dehiscence was defined as partial or complete disruption of the abdominal wound involving the fascial layer. Statistical analysis included univariate and multivariate logistic regression to identify independent predictors.
Results: Wound dehiscence occurred in 28 patients (6.67%). Significant risk factors in univariate analysis included anemia (p=0.001), hypoalbuminemia (p=0.004), diabetes mellitus (p=0.013), emergency surgery (p=0.002), surgical site infection (p<0.001), and operative time >180 minutes (p=0.016). Multivariate analysis identified hypoalbuminemia (OR=3.96; p=0.005), emergency surgery (OR=2.73; p=0.028), and surgical site infection (OR=5.81; p<0.001) as independent predictors of wound dehiscence.
Conclusion: Wound dehiscence is a multifactorial complication with preventable risk factors. Hypoalbuminemia, emergency surgery, and postoperative infection were found to be the most significant predictors. Preoperative nutritional optimization, rigorous aseptic practices, and close monitoring of high-risk patients are essential strategies to reduce its incidence and improve surgical outcomes.
References
2. Choudhary N, et al. A prospective study of wound dehiscence in emergency laparotomies. Int Surg J. 2021;8(6):1754–1759.
3. Khattry N, et al. Serum albumin as an indicator of wound healing postoperatively. J Postgrad Med. 2018;64(2):101–105.
4. Bhatnagar AM, et al. Role of serum albumin as predictor of wound complications. Indian J Med Sci. 2020;74(3):36–39.
5. Togo S, et al. Risk factors for wound dehiscence after abdominal surgery. Surg Today. 2011;41(5):681–685.
6. Gupta S, et al. Predictive factors of wound dehiscence after abdominal surgeries: a tertiary centre study. Int J Surg Sci. 2019;6(4):28–31.
7. Van Ramshorst GH, Nieuwenhuizen J, Hop WC, Arends P, Boom J, Jeekel J, Lange JF. Risk factors for abdominal wound dehiscence in adults: a case–control study. World J Surg. 2010;34(2):409–415.
8. Owens CD, Stoessel K. Surgical site infections: epidemiology, microbiology, and prevention. J Hosp Infect. 2008;70(Suppl 2):3–10.
9. Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Guideline for prevention of surgical site infection, 1999. Infect Control Hosp Epidemiol. 1999;20(4):247–278.
10. Srivastava S, et al. Study of wound dehiscence in abdominal surgery: role of modifiable risk factors. J Med Sci Clin Res. 2022;10(8):123–128.
11. Joscelyn RC, et al. Impact of anemia and transfusion on surgical site infection. Transfusion. 2014;54(1):237–246.
12. Van Ramshorst GH, et al. Risk factors for abdominal wound dehiscence in adults: a case–control study. World J Surg. 2010;34(2):409–415.
13. Latha K, et al. Postoperative wound complications and factors affecting wound healing. J Clin Diagn Res. 2015;9(6):PC01–PC03.
14. Ellis H. Wound healing and repair. In: Morris PJ, Wood WC, editors. Oxford Textbook of Surgery. 2nd ed. Oxford University Press; 2000.
15. Israelsson LA. Preventing and treating wound dehiscence after midline laparotomy. Surgeon. 2003;1(4):214–217.
16. Kumar A, Sharma V, Goyal D. Wound dehiscence: still a persistent problem in general surgery. Int Surg J. 2020;7(8):2575–2579.