FETOMATERNAL OUTCOME IN PREGNANCY WITH GESTATIONAL THROMBOCYTOPENIA

Main Article Content

Dr. Aishwarya Meshram
Dr. Azmat Jahan Mantoo
Prof. Dr. Cimona Lyn Saldanha
Dr Umer Hamid

Keywords

Gestational thrombocytopenia, maternal outcome, fetal outcome

Abstract

BACKGROUND : Thrombocytopenia is second most common hematological abnormality during pregnancy,  and is  found to complicate 7% to 8% of pregnancy in India. Thrombocytopenia in pregnancy may be an isolated findings or it may be associated with systemic disorders  like severe preeclampsia , HELLP syndrome(hemolysis, elevated liver enzymes, low platelets), or AFLP(acute fatty liver of pregnancy).


OBJECTIVE : To study the cases of thrombocytopenia during pregnancy and its effect on feto-maternal outcome.


MATERIAL AND METHODS: A prospective observational study was carried out in tertiary hospital, 422 pregnant women who attended the antenatal clinic regularly were enrolled ( >30 weeks of gestation). Out of 422 pregnant women, n=211 were women with normal platelet count were taken as control group and those with low count (<150×109/L) ,n= 211 were included in the study group.


RESULTS: the mean age of study group was 28.65±2.67 years and in control group was28.87±2.61 years.maternal and perinatal complications like intra op oozing(21.32%), PIH(22.75%), need for transfusion (22%,)hematoma formation(7%), neonatal jaundice (17.06%),neonatal thrombocytopenia(17.53%), birth asphyxia(9.04%),NICU admission(17.53%), need for resuscitation (30.33%),low apgar[<7](32.23%) etc. were more in patients with thrombocytopenia as compared to  their age and parity matched controls.


CONCLUSION: Study results showed , pregnancies with gestational thrombocytopenia were at higher risk of low Apgar scores, higher rate of admission to the  NICU, intracranial hemorrhage , neonatal death or adverse maternal outco×me as compared to the control group.

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