INFLUENCE OF VITAMIN D SUPPLEMENTATION ON PROTEINURIA IN TYPE 2 DIABETES
Main Article Content
Keywords
Vitamin D, Proteinuria, Type 2 Diabetes Mellitus, Diabetic Nephropathy, Supplementation
Abstract
Introduction: Proteinuria and progressive damage to the kidneys are the main reasons that T2DM can cause diabetic nephropathy. T2DM patients often lack vitamin D, which could be related to renal problems.
Objective: To evaluate the influence of vitamin D supplementation on proteinuria in patients with type 2 diabetes.
Materials and Methods: The study was designed as a prospective study and carried out at Lady Reading Hospital, Peshawar, Pakistan, from January 2024 to June 2024. The study included a total of 60 patients with type 2 diabetes mellitus (T2DM) and proteinuria who had vitamin D deficiency. For six months, the person received vitamin D3 supplements with 50,000 IU of cholecalciferol each week. Doctors tested proteinuria, 25-hydroxyvitamin D, HbA1c and renal function parameters at the start and the end of the supplementation period.
Results: Supplementing with vitamin D reduced proteinuria by 30% significantly (p<0.01) and improved vitamin D levels and blood glucose, with no reported adverse effects.
Conclusion: Taking vitamin D supplements decreases proteinuria and improves how the body handles metabolism for T2DM patients.
References
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Dr Tanveer Hassan
Postgraduate Resident, Department of Medicine, Lady Reading Hospital, Peshawar, Pakistan
Dr.Shamila Qamar Rana
Department of Obstetrics & Gynaecology, Shaikh Zayed Hospital Lahore, Pakistan
Dr Hafiz Faisal Munir Qamar
Department of Nephrology, Ali Fatima Hospital Lahore, Pakistan
Dr Muhammad Zoaib Khan
Department of Nephrology, Lady Reading Hospital, Peshawar, Pakistan