ASSESSMENT OF EXERCISE INDUCED GLYCEMIC VARIATIONS AMONG YOUNG ADULTS WITH VARYING BODY MASS INDEX
Main Article Content
Keywords
Exercise, Glycemic Variations, Young Adults, Body Mass Index
Abstract
Background: Exercise enhances glucose uptake in skeletal muscles independently of insulin by increasing the translocation of glucose transporter type 4 (GLUT4) to the cell membrane, thus promoting a decrease in circulating blood glucose levels. However, the magnitude of this glycemic response can vary depending on factors such as the intensity and duration of the exercise, the individual’s baseline glucose levels, and importantly, their body composition, especially BMI. Material & Methods: A Randomized Control Trial was conducted over a period of one year among the students of GSVM Medical College, Kanpur, in the Yoga and Exercise Lab of Physiology Department. All the physical parameters like age(years), height(cm), weight (kg) and blood pressure(mm Hg) were recorded initially in all the volunteers included in the study. The subjects were divided into two groups randomly to see, if there exists any correlation between the serum glucose levels and BMI.
Results: The exercise group showed a highly significant decrease in serum random blood glucose levels after 12 weeks (t = 8.51, p < 0.001), while the control group showed no significant change (t = -1.71, p = 0.096). This indicates that exercise effectively reduced blood glucose levels.
Conclusion: This study demonstrates that exercise significantly reduces blood glucose levels in young adults, with more pronounced effects in individuals with normal BMI. While all participants benefited to some extent, those with higher BMI showed a blunted glycemic response, underlining the need for tailored interventions.
References
2. Hawley, J. A., & Lessard, S. J. (2008). Exercise training-induced improvements in insulin action. Acta Physiologica, 192(1), 127–135. https://doi.org/10.1111/j.1748-1716.2007.01783.x
3. Bird, S. R., & Hawley, J. A. (2017). Update on the effects of physical activity on insulin sensitivity in humans. BMJ Open Sport & Exercise Medicine, 3(1), e000143. https://doi.org/10.1136/bmjsem-2017-000143
4. Francois, M. E., & Little, J. P. (2015). Effectiveness and safety of high-intensity interval training in patients with type 2 diabetes. Diabetes Spectrum, 28(1), 39-44. https://doi.org/10.2337/diaspect.28.1.39
5. DeFronzo, R. A., & Tripathy, D. (2009). Skeletal muscle insulin resistance is the primary defect in type 2 diabetes. Diabetes Care, 32(suppl_2), S157–S163.
https://doi.org/10.2337/dc09-S302
6. Kahn, B. B., Hull, R. L., & Utzschneider, K. M. (2006). Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature, 444(7121), 840–846.
https://doi.org/10.1038/nature05482
7. Karstoft, K., Winding, K., Knudsen, S. H., et al. (2013). The effects of free-living interval-walking training on glycemic control, body composition, and physical fitness in type 2 diabetic patients. Diabetes Care, 36(2), 228–236. https://doi.org/10.2337/dc12-0658
8. Goodpaster, B. H., Kelley, D. E., Wing, R. R., Meier, A., & Thaete, F. L. (2001). Effects of weight loss on regional fat distribution and insulin sensitivity in obesity. Diabetes, 48(4), 839–847. https://doi.org/10.2337/diabetes.48.4.839
9. Ng, M., Fleming, T., Robinson, M., et al. (2014). Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis. The Lancet, 384(9945), 766–781. https://doi.org/10.1016/S0140-6736(14)60460-8
10. Harrisons Principles of Internal Medicine Chapter 402 Evaluation and Management of Obesity Robert F Kushner
11. WHO Guidelines On Physical Activity And Sedentary Behaviour
12. World Health Organization(WHO) grading of exercise Ghai’s Textbook of Practical Physiology
13. Gupta A. Correlationship of cardiovascular efficiency with regular physical activity in first-year MBBS students. Int J Physiol. 2017;5(2):
14. Colberg, S. R., Sigal, R. J., Yardley, J. E., et al. (2016). Physical Activity/Exercise and Diabetes: A Position Statement of the American Diabetes Association. Diabetes Care, 39(11), 2065–2079. https://doi.org/10.2337/dc16-1728
15. Hawley, J. A., & Lessard, S. J. (2008). Exercise training-induced improvements in insulin action. Acta Physiologica, 192(1), 127–135. https://doi.org/10.1111/j.1748-1716.2007.01783.x
16. DeFronzo, R. A., & Tripathy, D. (2009). Skeletal muscle insulin resistance is the primary defect in type 2 diabetes. Diabetes Care, 32(Suppl 2), S157–S163.
https://doi.org/10.2337/dc09-S302
17. Kahn, B. B., Hull, R. L., & Utzschneider, K. M. (2006). Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature, 444(7121), 840–846.
https://doi.org/10.1038/nature05482
18. Goodpaster, B. H., Kelley, D. E., Wing, R. R., Meier, A., & Thaete, F. L. (2001). Effects of weight loss on regional fat distribution and insulin sensitivity in obesity. Diabetes, 48(4), 839–847. https://doi.org/10.2337/diabetes.48.4.839
19. Ng, M., Fleming, T., Robinson, M., et al. (2014). Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis. The Lancet, 384(9945), 766–781. https://doi.org/10.1016/S0140-6736(14)60460-8