EVALUATION OF ANTIBIOTIC PRESCRIBING PATTERNS FOR ACUTE OTITIS MEDIA IN ENT DEPARTMENT OF A TERTIARY CARE HOSPITAL

Main Article Content

Dr. Ramya K.N.
Dr. Harshitha C.
Dr. Harshavardhana K.N.

Keywords

Acute Otitis Media, Antibiotic Prescribing Patterns, Antimicrobial Stewardship, Amoxicillin, Broad-Spectrum Antibiotics, ENT Department,  Paediatric Infections.

Abstract

Background


Particularly in children under five, Acute Otitis Media (AOM) is a common and serious health problem that is a major contributor to the prescription of antibiotics in outpatient settings. Antibiotics are commonly prescribed without adequate diagnostic confirmation, despite the fact that many cases are viral and self-limiting. This contributes to the growing issue of antimicrobial resistance (AMR). Though differences in prescribing practices continue to exist across healthcare settings, clinical guidelines advise a more conservative approach in non-severe cases. To encourage sensible antibiotic use and improve antimicrobial stewardship, it is imperative to assess these trends.


Aim


The aim of this study was to determine possible areas for antimicrobial stewardship improvement by analyzing the antibiotic prescribing patterns for AOM (Acute Otitis Media) in the ENT department of a tertiary care hospital and their compliance with accepted clinical guidelines.


Methodology


300 patient records with an AOM diagnosis were the subject of this retrospective cross-sectional study which was conducted between June 2024 to December 2024. We gathered and examined information on demographics, antibiotic prescriptions, dosage, route, and duration. The American Academy of Paediatrics and World Health Organization's established guidelines were used to evaluate prescribing patterns.


Result


Out of the 300 patients, 40% were children younger than five. The most often prescribed antibiotics were amoxicillin (36.7%) and amoxicillin-clavulanic acid (16.7%). Most patients (60%) received antibiotics for 6–7 days, and 86.7% preferred oral administration. 61.7% of prescriptions were found to be in compliance with treatment guidelines, whereas 38.3% displayed partial or total non-compliance, which included prolonged therapy and excessive use of broad-spectrum antibiotics


 


 


Conclusion


While the majority of antibiotic prescriptions adhered to recommended practices, there are some notable exceptions that could lead to antibiotic resistance. To encourage sensible antibiotic use in AOM management, improved antimicrobial stewardship and clinician education are essential.

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References

[1] Lieberthal AS, Carroll AE, Chonmaitree T, et al. The diagnosis and management of acute otitis media. Pediatrics 2013;131(3):e964-99.
[2] Monasta L, Ronfani L, Marchetti F, et al. Burden of disease caused by otitis media: systematic review and global estimates. PLoS One 2012;7(4):e36226.
[3] Venekamp RP, Sanders SL, Glasziou PP, et al. Antibiotics for acute otitis media in children. Cochrane Database Syst Rev 2015;(6):CD000219.
[4] World Health Organization. Antimicrobial resistance. 2020. Available from:
https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance
[5] McCaig LF, Hughes JM. Trends in antimicrobial drug prescribing among office-based physicians in the United States. JAMA 1995;273(3):214-9.
[6] Fleming-Dutra KE, Hersh AL, Shapiro DJ, et al. Prevalence of inappropriate antibiotic prescriptions among US ambulatory care visits, 2010–2011. JAMA 2016;315(17):1864-73.
[7] Schilder AG, Chonmaitree T, Cripps AW, et al. Otitis media. Nat Rev Dis Primers 2016;2:16063.
[8] McDonald S, Langton Hewer CD, Nunez DA. Delayed antibiotics for respiratory infections including otitis media. BMJ Clin Evid 2015;2015:0507.
[9] Centers for Disease Control and Prevention (CDC). Outpatient antibiotic prescriptions-United States, 2019. Available from: https://www.cdc.gov/antibiotic-use/community/programs-measurement/measuring-antibiotic-prescribing.html
[10] Spiro DM, Tay KY, Arnold DH, etal. Wait-and-see prescription for the treatment of acute otitis media: a randomized controlled trial. JAMA 2006;296(10):1235-41.
[11] Hersh AL, Shapiro DJ, Pavia AT, et al. Antibiotic prescribing in ambulatory pediatrics in the United States. Pediatrics 2011;128(6):1053-61.
[12] Vaz LE, Kleinman KP, Raebel MA, et al. Recent trends in outpatient antibiotic use in children. Pediatrics 2014;133(3):375-85.
[13] Dyar OJ, Huttner B, Schouten J, et al. What is antimicrobial stewardship? Clin Microbiol Infect 2017;23(11):793-8.
[14] Holloway KA, Ivanovska V, Wagner AK, et al. Have we improved use of medicines in developing and transitional countries and do we know how to? Two decades of evidence. Trop Med Int Health 2013;18(6):656–64.
[15] Lieberthal AS, Carroll AE, Chonmaitree T, et al. The diagnosis and management of acute otitis media. Pediatrics 2013;131(3):e964-99.
[16] Cabral C, Lucas PJ, Ingram J, Hay AD, Horwood J. “It's safer to…” parent consulting and clinician antibiotic prescribing decisions for children with respiratory tract infections: An analysis across four qualitative studies. Social Science & Medicine 2015;136:156-64.
[17] Chandy SJ, Naik GS, Balasubramanian S, et al. High cost burden and health consequences of inappropriate use of antibiotics for pediatric acute otitis media in India. Health Policy Plan 2018;33(6):654-61.
[18] Laxminarayan R, Matsoso P, Pant S, et al. Access to effective antimicrobials: a worldwide challenge. Lancet 2016;387(10014):168-75.
[19] Hoberman A, Paradise JL, Rockette HE, et al. Shortened antimicrobial treatment for acute otitis media in young children. N Engl J Med 2016;375(25):2446-56.
[20] Monasta L, Ronfani L, Marchetti F, et al. Burden of disease caused by otitis media: systematic review and global estimates. PLoS One 2012;7(4):e36226.