FREQUENCY OF CAUSES OF INHALATION THERAPY FAILURE IN ASTHMA PATIENTS PRESENTING TO A TERTIARY CARE HOSPITAL IN PESHAWAR
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Keywords
Asthma, Inhalation Therapy, Patient Compliance, Drug Administration Routes, Health Knowledge, Treatment Failure
Abstract
Objective: To determine the frequency of various causes leading to the failure of inhalation therapy in asthma patients presenting to a tertiary care hospital in Peshawar.
Methods: This descriptive cross-sectional study was conducted at the Department of Pulmonology, Hayatabad Medical Complex, Peshawar, from May, 2022 to October, 2022. A total of 100 asthma patients aged 14 to 65 years on inhalation therapy were enrolled through non-probability consecutive sampling. Data were collected using a structured proforma to identify potential causes of inhalation therapy failure, including non-adherence, inappropriate therapy, incorrect inhalation technique, comorbidities, and poor disease awareness. Data were analyzed using SPSS version 26. Continuous variables were summarized as mean ± SD or median (IQR), while categorical variables were reported as n (%). Chi-square or Fisher’s exact tests were applied for post-stratification analysis; a p-value < 0.05 was considered statistically significant.
Results: The mean age of patients was 39.35 ± 15.64 years. The most frequent cause of inhalation therapy failure was incorrect technique in 31 (31.0%) patients, followed by inappropriate therapy in 25 (25.0%), poor awareness in 25 (25.0%), and non-adherence in 21 (21.0%). No statistically significant association was observed between these causes and demographic or clinical variables including age group, gender, asthma severity, therapy type, or residential status (p > 0.05).
Conclusions: Failure of inhalation therapy in asthma patients was most commonly linked to incorrect technique and modifiable behavioral factors rather than demographic or clinical characteristics.
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Muhammad Zubair Khan
Medical Officer, Neurology Unit, MTI-HMC, Peshawar KPK
Tanveer Ul Haq
Specialist Registrar Medical ICU Hayatabad Medical Complex Peshawar
Muhammad Awais Khan
Specialist Registrar Medical A Unit HMC
Asif Ur Rehman
Lecturer Community Medicine Nowshera Medical College
Abdurehman
Registrar ICU PGH hospital Peshawar
Sanaullah
PGR pulmonology HMC peshawar