SARCOPENIA IN CKD V PRE-DIALYSIS PATIENTS USING HANDGRIP STRENGTH
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Keywords
Sarcopenia, Handgrip Strength, Chronic Kidney Disease, Pre-Dialysis, Malnutrition
Abstract
Introduction: Sarcopenia means the loss of muscle mass, which has a higher prevalence in pre-dialysis CKD stage 5 patients and leads to increased morbidity and mortality. Handgrip strength (HGS) is also beneficial for the diagnosis of the mentioned pathology.
Objective: To evaluate HGS as a diagnostic and prognostic tool for sarcopenia in pre-dialysis CKD stage 5 patients in a Pakistani hospital.
Materials and Method: This cross-sectional study was conducted at Ali Fatima Hospital, Bhobatian Chowk, Raiwind Road, Lahore, Pakistan from January, 2024 to June, 2024 to recruit 90 patients with pre-dialysis CKD stage 5 (with ages between 20-60 years). HGS was assessed with a dynamometer, and sarcopenia was diagnosed according to the EWGSOP2 (<27 kg for men, <16 kg for women).
Results: Sarcopenia was present in 46.67% of the patients, with higher odds detected in females 56.25% and patients 50 years and above 60%. Significant difference is found in the mean HGS between the sarcopenic and non-sarcopenic groups (16.45 ± 4.82 kg vs 24.88 ± 7.12 kg P<0.001). Malnutrition was noted in 60 percent of the sarcopenic patients when the comparison was made (p<0.05).
Conclusion: HGS can also be used to diagnose sarcopenia in pre-dialysis CKD patients and initiate timely treatment.
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Dr. Hafiz Faisal Munir Qamar
Registrar Nephrology, Ali Fatima Hospital, Bhobatian Chowk, Raiwind Road, Lahore, Pakistan.
Dr. Muhammad Mohsin Riaz
Assistant Professor of Nephrology, Ali Fatima Hospital, Bhobatian Chowk, Raiwind Road, Lahore, Pakistan.
Dr. Muhammad Bilal Basit
Senior Registrar Nephrology, Fatima Memorial Hospital, Lahore, Pakistan
Dr. Nabiha Rizvi
Assistant Professor of Nephrology, Lahore Medical and Dental College Lahore, Pakistan.
Dr. Aqeel Ahmed
Senior Registrar Nephrology, Gujranwala Medical College Teaching Hospital, Gujranwala, Pakistan.
Dr. Muhammad Asif
Senior Registrar Nephrology, DG Khan Medical College Dera Ghazi Khan, Pakistan
Dr. Hafiz Nauman Munir Saqib
Medical Officer, Nephrology, Evercare Hospital, Lahore, Pakistan.