Executive Functioning and Working Memory Deficits on the CANTABĀ® Among Children with Prenatal Alcohol Exposure
J Popul Ther Clin Pharmacol Vol 18 (1):e44-e53; January 28, 2011
Original Research
Carmen Rasmussen, Maryam Soleimani, Jacqueline Pei

Background
Children with prenatal alcohol exposure (PAE) and Fetal Alcohol Spectrum Disorders (FASD) display numerous neuropsychological impairments, including deficits on measures of executive functioning (EF) and working memory.

Objectives
The goal of this project was to examine whether children with PAE and FASD demonstrate EF and working memory deficits on the CANTAB® (a computerized neuropsychological test).

Methods
Twenty-four children with PAE and 26 control children were tested on the CANTAB®.

Results
Children with PAE demonstrated deficits in the areas of executive functioning, working memory, and attention. Among the PAE group, those with FASD were specifically impaired on working memory capacity.

Conclusions
The CANTAB® is a useful tool for detecting neurobehavioral deficits in children with PAE.

Key Words: Fetal Alcohol Spectrum Disorder (FASD); Executive function (EF); memory; CANTAB®

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